Title:
GENETICALLY ENGINEERED CYANOBACTERIA
Document Type and Number:
WIPO Patent Application WO/2012/116345
Kind Code:
A3
Abstract:
The disclosed embodiments provide cyanobacteria spp. that have been genetically engineered to have increased production of carbon-based products of interest. These genetically engineered hosts efficiently convert carbon dioxide and light into carbon-based products of interest such as long chained hydrocarbons. Several constructs containing polynucleotides encoding enzymes active in the metabolic pathways of cyanobacteria are disclosed. In many instances, the cyanobacteria strains have been further genetically modified to optimize production of the carbon-based products of interest. The optimization includes both up- regulation and down-regulation of particular genes.
Inventors:
ZHOU RUANBAO (US)
GIBBONS WILLIAM (US)
GIBBONS WILLIAM (US)
Application Number:
PCT/US2012/026652
Publication Date:
November 08, 2012
Filing Date:
February 24, 2012
Export Citation:
Assignee:
UNIV SOUTH DAKOTA (US)
ZHOU RUANBAO (US)
GIBBONS WILLIAM (US)
ZHOU RUANBAO (US)
GIBBONS WILLIAM (US)
International Classes:
C12N1/13; C12N15/52; C12N15/74; C12P5/00; C12P7/02; C12R1/89
Domestic Patent References:
| WO2010093365A1 | 2010-08-19 | |||
| WO2011006137A2 | 2011-01-13 |
Foreign References:
| US20110020867A1 | 2011-01-27 | |||
| US20090155871A1 | 2009-06-18 |
Attorney, Agent or Firm:
COX, Kathryn (Suite 101Atlanta, GA, US)
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