Title:
GENETICALLY MODIFIED IMMUNODEFICIENT NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC SIRPα/CD47
Document Type and Number:
WIPO Patent Application WO/2021/136537
Kind Code:
A1
Abstract:
The genetically modified immunodeficient animals which express a human or chimeric (e.g., humanized) SIRRα and/or human or chimeric (e.g., humanized) CD47, and methods of use thereof.
Inventors:
SHEN YUELEI (CN)
BAI YANG (CN)
YAO JIAWEI (CN)
GUO CHAOSHE (CN)
ZHANG MEILING (CN)
HUANG RUI (CN)
GUO YANAN (CN)
SHANG CHENGZHANG (CN)
BAI YANG (CN)
YAO JIAWEI (CN)
GUO CHAOSHE (CN)
ZHANG MEILING (CN)
HUANG RUI (CN)
GUO YANAN (CN)
SHANG CHENGZHANG (CN)
Application Number:
PCT/CN2020/142546
Publication Date:
July 08, 2021
Filing Date:
December 31, 2020
Export Citation:
Assignee:
BIOCYTOGEN PHARMACEUTICALS BEIJING CO LTD (CN)
International Classes:
A01K67/027; C07K14/705; C12N15/90
Domestic Patent References:
| WO2018177441A1 | 2018-10-04 | |||
| WO2019095358A1 | 2019-05-23 | |||
| WO2001048020A1 | 2001-07-05 | |||
| WO2016179399A1 | 2016-11-10 |
Foreign References:
| CN108531487A | 2018-09-14 | |||
| CN108467873A | 2018-08-31 | |||
| CN108588126A | 2018-09-28 | |||
| CN105592695A | 2016-05-18 | |||
| CN107205368A | 2017-09-26 | |||
| CN108531487A | 2018-09-14 | |||
| CN108467873A | 2018-08-31 | |||
| CN108588126A | 2018-09-28 | |||
| CN109735498A | 2019-05-10 |
Attorney, Agent or Firm:
BEIJING LINKTEC IP LAW FIRM (SPECIAL GENERAL PARTNERSHIP) (CN)
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