Title:
GENIPIN DERIVATIVES AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO2004089926
Kind Code:
A8
Abstract:
Genipin derivatives and pharmaceutical compositions thereof that inhibit the activity of uncoupling protein-2 (UCP2) and are useful in treating deficient first-phase insulin secretion, non-insulin dependent diabetes mellitus, and ischemia in a mammal are disclosed.
Inventors:
ZHANG CHEN-YU (US)
LOWELL BRADFORD B (US)
PORCO JOHN A JR (US)
SHEN RUICHAO (US)
LIN CHENG TING (US)
KRAUSS STEFAN (US)
LOWELL BRADFORD B (US)
PORCO JOHN A JR (US)
SHEN RUICHAO (US)
LIN CHENG TING (US)
KRAUSS STEFAN (US)
Application Number:
PCT/US2004/009957
Publication Date:
January 20, 2005
Filing Date:
March 31, 2004
Export Citation:
Assignee:
BETH ISRAEL HOSPITAL (US)
UNIV BOSTON (US)
ZHANG CHEN-YU (US)
LOWELL BRADFORD B (US)
PORCO JOHN A JR (US)
SHEN RUICHAO (US)
LIN CHENG TING (US)
KRAUSS STEFAN (US)
UNIV BOSTON (US)
ZHANG CHEN-YU (US)
LOWELL BRADFORD B (US)
PORCO JOHN A JR (US)
SHEN RUICHAO (US)
LIN CHENG TING (US)
KRAUSS STEFAN (US)
International Classes:
A61K31/352; C07D211/90; C07D221/04; C07D309/32; C07D311/94; C07D491/04; C07D493/04; C07D493/06; (IPC1-7): C07D311/94
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