Title:
GINSENOSIDE CHEMOTHERAPY
Document Type and Number:
WIPO Patent Application WO2001082908
Kind Code:
A3
Abstract:
The invention provides for the use of ginsenoside Rh2 in pharmaceutical compositions used in methods of inhibiting the multiplication of cancer cells, and methods of treating cancer in patients, comprising administering to such patients therapeutically and synergistically effective amounts of Rh2 in combination with a chemotherapeutic selected from the group consisting of paclitaxel and mitoxantrone. The cancer cells to be treated may be multidrug resistant. The cancer cells may for example be prostate cancer cells or breast cancer cells.
Inventors:
JIA WILLIAM (CA)
Application Number:
PCT/CA2001/000642
Publication Date:
August 08, 2002
Filing Date:
May 01, 2001
Export Citation:
Assignee:
UNIV BRITISH COLUMBIA (CA)
JIA WILLIAM (CA)
JIA WILLIAM (CA)
International Classes:
A61K31/337; A61K31/7004; A61K33/24; (IPC1-7): A61K35/78; A61K31/70; A61K31/335; A61K31/135
Other References:
DUDA R B ET AL: "American ginseng and breast cancer therapeutic agents synergistically inhibit MCF-7 breast cancer cell growth.", JOURNAL OF SURGICAL ONCOLOGY, (1999). VOL. 72, NO. 4, PP. 230-9. JOURNAL CODE: K79. ISSN: 0022-4790., XP001035053
DATABASE WPI Section Ch Week 199703, Derwent World Patents Index; Class B01, AN 1997-029530, XP002184631
HAN, RUI: "Recent progress in the study of anticancer drugs originating from plants and traditional medicines in China", CHIN. MED. SCI. J. (1994), 9(1), 61-9, XP001035070
HAN R: "Highlight on the studies of anticancer drugs derived from plants in China", STEM CELLS, (1994). VOL. 12, NO. 1, PP. 53-63. JOURNAL CODE: BN2. ISSN: 1066-5099., XP000933942
DATABASE WPI Section Ch Week 199703, Derwent World Patents Index; Class B01, AN 1997-029530, XP002184631
HAN, RUI: "Recent progress in the study of anticancer drugs originating from plants and traditional medicines in China", CHIN. MED. SCI. J. (1994), 9(1), 61-9, XP001035070
HAN R: "Highlight on the studies of anticancer drugs derived from plants in China", STEM CELLS, (1994). VOL. 12, NO. 1, PP. 53-63. JOURNAL CODE: BN2. ISSN: 1066-5099., XP000933942
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