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Title:
GLP-1 AGONIST INTERMEDIATE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE
Document Type and Number:
WIPO Patent Application WO/2023/125896
Kind Code:
A1
Abstract:
A preparation method for a compound represented by formula (I) and an intermediate thereof. The method has the advantages of mild reaction conditions, simple operation, high reaction yield, high product purity, convenience in post-treatment and suitability for industrial production.

Inventors:
FAN JIANG (CN)
DOU YING (CN)
WANG ZHIGANG (CN)
ZHU FENGFEI (CN)
Application Number:
PCT/CN2022/143760
Publication Date:
July 06, 2023
Filing Date:
December 30, 2022
Export Citation:
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Assignee:
HAISCO PHARMACEUTICAL GROUP CO LTD (CN)
International Classes:
C07D513/04; A61K31/395; A61P3/10
Domestic Patent References:
WO2021244645A12021-12-09
WO2021249492A12021-12-16
WO2019134661A12019-07-11
WO2022135572A12022-06-30
Foreign References:
CN113801136A2021-12-17
Other References:
IDON BRIAN, NAZIR KHAN, BEE LAM LIM: "A Convenient Synthesis of Thieno[2,3-d]limidazoles", JOURNAL OF THE CHEMICAL SOCIETY, CHEMICAL COMMUNICATIONS, vol. 20, 1 January 1985 (1985-01-01), pages 1428 - 1429, XP093074508
WAUCHOPE, O. R. ET AL.: "Synthesis and biological evaluation of a series of thieno-expanded tricyclic purine 2'-deoxy nucleoside analogues", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 20, 12 March 2012 (2012-03-12), XP028412830, DOI: 10.1016/j.bmc.2012.03.004
Attorney, Agent or Firm:
BEIJING SANYOU INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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