Title:
GLP-1 SECRETAGOGUE
Document Type and Number:
WIPO Patent Application WO/2020/218383
Kind Code:
A1
Abstract:
Development of a novel GLP-secretagogue for promoting secretion of GLP-1 is anticipated. The present invention provides a GLP-secretagogue characterized by containing 2 ppm or more of mogroside.
Inventors:
URAI SOICHIRO (JP)
NAGAO KOJI (JP)
YOKOO YOSHIAKI (JP)
NAGAO KOJI (JP)
YOKOO YOSHIAKI (JP)
Application Number:
PCT/JP2020/017403
Publication Date:
October 29, 2020
Filing Date:
April 22, 2020
Export Citation:
Assignee:
SUNTORY HOLDINGS LTD (JP)
International Classes:
A61P3/04; A23L2/52; A23L33/105; A61K31/704; A61P3/10; C07J9/00
Domestic Patent References:
| WO2012054528A2 | 2012-04-26 |
Foreign References:
| CN105596401A | 2016-05-25 |
Other References:
QI, XIANGYANG ET AL.: "Mogrosides extract from Siraitia grosvenori scavenges free radicals in vitro and lowers oxidative stress, serum glucose and lipid levels in alloxan-induced diabetic mice", NUTRITION RESEARCH, vol. 28, no. 4, 2008, pages 278 - 284, XP022590902, ISSN: 0271-5317, DOI: 10.1016/j.nutres.2008.02.008
OHTSU, YOSHIAKI ET AL.: "Diverse signaling systems activated by the sweet taste receptor in human GLP-1-secreting cells", MOLECULAR AND CELLULAR ENDOCRINOLOGY, vol. 394, no. 1-2, 2014, pages 70 - 79, XP029053752, ISSN: 0303-7207, DOI: 10.1016/j.mce.2014.07.004
OHTSU, YOSHIAKI ET AL.: "Diverse signaling systems activated by the sweet taste receptor in human GLP-1-secreting cells", MOLECULAR AND CELLULAR ENDOCRINOLOGY, vol. 394, no. 1-2, 2014, pages 70 - 79, XP029053752, ISSN: 0303-7207, DOI: 10.1016/j.mce.2014.07.004
Attorney, Agent or Firm:
KOBAYASHI Hiroshi et al. (JP)
Download PDF: