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Title:
GLUCOPYRANOSYL DERIVATIVE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/149178
Kind Code:
A1
Abstract:
The present invention relates to a glucopyranosyl derivative and a use thereof. In particular, the present invention relates to a glucopyranosyl derivative that is used as an inhibitor of sodium-dependent glucose transporters (SGLTs), particularly being used as an inhibitor of sodium-dependent glucose transporter-1 (SGLT1), and a pharmaceutically acceptable salt or stereoisomer thereof, further relating to a pharmaceutical composition containing the derivative. The present invention further relates to a use of the compound and a pharmaceutical composition thereof in the preparation of a drug for treating diabetes and diabetes-related diseases.

Inventors:
GU, Zheng (Dongyangguang Hi-tech Park, Zhen An Road No. 368 Shang Sha, Chang An Tow, Dongguan Guangdong 1, 523871, CN)
WU, Wuyong (Dongyangguang Hi-tech Park, Zhen An Road No. 368 Shang Sha, Chang An Tow, Dongguan Guangdong 1, 523871, CN)
KANG, Panpan (Dongyangguang Hi-tech Park, Zhen An Road No. 368 Shang Sha, Chang An Tow, Dongguan Guangdong 1, 523871, CN)
QU, Tong (Dongyangguang Hi-tech Park, Zhen An Road No. 368 Shang Sha, Chang An Tow, Dongguan Guangdong 1, 523871, CN)
ZHANG, Zongyuan (Dongyangguang Hi-tech Park, Zhen An Road No. 368 Shang Sha, Chang An Tow, Dongguan Guangdong 1, 523871, CN)
HUANG, Weiming (Dongyangguang Hi-tech Park, Zhen An Road No. 368 Shang Sha, Chang An Tow, Dongguan Guangdong 1, 523871, CN)
WU, Tianyun (Dongyangguang Hi-tech Park, Zhen An Road No. 368 Shang Sha, Chang An Tow, Dongguan Guangdong 1, 523871, CN)
ZHANG, Yingjun (Dongyangguang Hi-tech Park, Zhen An Road No. 368 Shang Sha, Chang An Tow, Dongguan Guangdong 1, 523871, CN)
Application Number:
CN2019/073550
Publication Date:
August 08, 2019
Filing Date:
January 29, 2019
Export Citation:
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Assignee:
SUNSHINE LAKE PHARMA CO., LTD. (Northern Industrial Area, Songshan LakeDongguan, Guangdong 0, 523000, CN)
International Classes:
C07H9/04; A61K31/7048; A61P3/10; A61P5/50; A61P9/10; A61P27/02; C07D493/08
Domestic Patent References:
WO2013038429A22013-03-21
Foreign References:
CN105461762A2016-04-06
CN104854096A2015-08-19
CN104619713B2017-06-16
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