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Title:
GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2012/176804
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a compound having human SGLT2 inhibitory activity, a prodrug of the compound, a pharmacologically acceptable salt of the compound, and a pharmaceutical use of the compound. The present invention provides a compound which is represented by general formula (1) (wherein RA represents a hydrogen atom, a C1-6 alkyl group or the like; RB represents a C1-6 alkoxy group or the like; each of RC and RD independently represents a hydrogen atom, a halogen atom or the like; and n represents a number of 1-3) and has human SGLT2 inhibitory activity, a prodrug of the compound, or a pharmacologically acceptable salt of the compound. In addition, the compound of the present invention can be utilized as a therapeutic or prophylactic agent for diseases associated with high blood sugar.

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Inventors:
FUJIKURA HIDEKI (JP)
FUJIOKA MINORU (JP)
Application Number:
PCT/JP2012/065744
Publication Date:
December 27, 2012
Filing Date:
June 20, 2012
Export Citation:
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Assignee:
KISSEI PHARMACEUTICAL (JP)
FUJIKURA HIDEKI (JP)
FUJIOKA MINORU (JP)
International Classes:
C07H17/02; A61K31/155; A61K31/426; A61K31/64; A61K31/7056; A61K45/00; A61P3/10; A61P43/00
Domestic Patent References:
WO2002098893A12002-12-12
WO2004019958A12004-03-11
WO2004014932A12004-02-19
Foreign References:
JP2009203230A2009-09-10
JP2006510644A2006-03-30
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