GLUCOSE SENSOR ELECTRODE, PREPARATION METHOD THEREFOR AND USE THEREOF

WIPO Patent Application WO/2019/218562

A1

The present invention belongs to the technical field of medical apparatuses and instruments, and discloses a glucose sensor electrode, a preparation method therefor and the use thereof. The method involves: (1) performing an alkali heat treatment to form a nanoneedle-structured titanium dioxide on the surface of a titanium electrode; (2) forming micro-region grooves on a nanoneedle-structured titanium dioxide film layer to obtain a nanoneedle-structured titanium dioxide having a micropattern; (3) depositing a chlorine-doped polypyrrole in the grooves by using chronopotentiometry; (4) forming a nanocone-structured citric-acid-doped polypyrrole on the chlorine-doped polypyrrole by using chronopotentiometry; and (5) grafting an enzyme capable of detecting glucose to obtain the glucose sensor electrode. The glucose sensor electrode of the present invention is used for the rapid and sensitive detection of glucose. The present invention has a simple and stable process, is low in cost, efficiently grafts the enzyme capable of detecting glucose on the surface of the electrode, and has a higher reliability for detecting glucose; and the stability of the electrode is good.

NING CHENGYUN (CN)
WANG ZHEN'GAO (CN)
YU PENG (CN)
QIAN LEI (CN)
ZHOU ZHENGNAN (CN)
XING JUN (CN)
CHEN JUNQI (CN)
ZHOU LEI (CN)
TAN GUOXIN (CN)

PCT/CN2018/106842

November 21, 2019

September 21, 2018

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UNIV SOUTH CHINA TECH (CN)
UNIV GUANGDONG TECHNOLOGY (CN)

G01N27/327

CN102735727A	2012-10-17
CN1815215A	2006-08-09
CN102262114A	2011-11-30

GUANGZHOU HUAXUE INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)

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