Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
GLUTAMINE ACYL CYCLASE INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2017/071479
Kind Code:
A1
Abstract:
Disclosed is a glutamine acyl cyclase inhibitor, and the structure thereof is as shown in formula (I). The glutamine acyl cyclase inhibitor (QC inhibitor) provided in the present invention is designed according to the target enzyme protein activity center crystal structure, shows good selectivity and specificity, and has a higher druggability; and the maternal structure thereof is richer, and same has a good water solubility, a good transmembrane performance, and a higher activity.

Inventors:
WU HAIQIANG (CN)
LIU ZHIGANG (CN)
HE ZHENDAN (CN)
ZHENG YIZHI (CN)
ZOU YONGDONG (CN)
Application Number:
PCT/CN2016/101995
Publication Date:
May 04, 2017
Filing Date:
October 13, 2016
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
UNIV SHENZHEN (CN)
International Classes:
C07D233/61; A61P1/16; A61P19/02; A61P19/04; A61P25/28; A61P29/00; A61P35/00; A61P37/02
Domestic Patent References:
WO2008065141A12008-06-05
Foreign References:
CN105384692A2016-03-09
CN1918131A2007-02-21
CN105384691A2016-03-09
Attorney, Agent or Firm:
JOHNSON INTELLECTUAL PROPERTY AGENCY(SHENZHEN) (CN)
Download PDF: