Title:
GLUTARYL AMIDASES AND THEIR USES
Document Type and Number:
WIPO Patent Application WO2005054452
Kind Code:
A3
Abstract:
The invention relates to a new class of isolated, single or multiple mutated glutaryl amidases from Pseudomonas SY-77, or a functional part, derivative or analogue thereof. The invention also relates to a method for preparing 7-aminocephalosporanic acid from cephalosporin C, using a glutaryl amidase according to the invention. The invention also provides a method for preparing aminodesacetoxycephalosporanic acid.
Inventors:
SIO CHARLES FREDRIK (NL)
OTTEN LUDWINA GERHARDA (NL)
COOL ROBBERT HANS (NL)
QUAX WILHELMUS JOHANNES (NL)
OTTEN LUDWINA GERHARDA (NL)
COOL ROBBERT HANS (NL)
QUAX WILHELMUS JOHANNES (NL)
Application Number:
PCT/NL2004/000850
Publication Date:
April 06, 2006
Filing Date:
December 06, 2004
Export Citation:
Assignee:
STICHTING TECH WETENSCHAPP (NL)
SIO CHARLES FREDRIK (NL)
OTTEN LUDWINA GERHARDA (NL)
COOL ROBBERT HANS (NL)
QUAX WILHELMUS JOHANNES (NL)
SIO CHARLES FREDRIK (NL)
OTTEN LUDWINA GERHARDA (NL)
COOL ROBBERT HANS (NL)
QUAX WILHELMUS JOHANNES (NL)
International Classes:
C12N9/84; C12N15/10; C12N15/63; C12P35/02
Foreign References:
| EP0453048A1 | 1991-10-23 |
Other References:
OTTEN LINDA G ET AL: "Altering the substrate specificity of cephalosporin acylase by directed evolution of the beta-subunit.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 277, no. 44, 1 November 2002 (2002-11-01), pages 42121 - 42127, XP002288438, ISSN: 0021-9258
Download PDF: