Title:
GLYCEROL-3-PHOSPHATE O-ACYL TRANSFERASE PROMOTER FOR GENE EXPRESSION IN OLEAGINOUS YEAST
Document Type and Number:
WIPO Patent Application WO2006031937
Kind Code:
A3
Abstract:
The promoter region associated with the Yarrowia lipolytica glycerol-3-phosphate O-acyltransferase (gpat) gene has been found to be particularly effective for the expression of heterologous genes in oleaginous yeast. The promoter regions of the instant invention have been shown to be suitable to drive high-level expression of genes involved in the production of ?-3 and ?-6 fatty acids.
Inventors:
XUE ZHIXIONG (US)
ZHU QUINN QUN (US)
ZHU QUINN QUN (US)
Application Number:
PCT/US2005/032860
Publication Date:
May 11, 2006
Filing Date:
September 14, 2005
Export Citation:
Assignee:
DU PONT (US)
XUE ZHIXIONG (US)
ZHU QUINN QUN (US)
XUE ZHIXIONG (US)
ZHU QUINN QUN (US)
International Classes:
C12P21/06; C12P7/64
Foreign References:
| US20060035351A1 | 2006-02-16 |
Other References:
MADZAK C ET AL: "Heterologous Protein Expression and Secretion in the Non-conventional Yeast Yarrowia lipolytica: A Review.", J OF BIOTECH., vol. 109, no. 1-2, April 2004 (2004-04-01), pages 63 - 81, XP002995176
Download PDF: