Title:
GLYCOCONJUGATE VACCINES CONTAINING PEPTIDOGLYCAN
Document Type and Number:
WIPO Patent Application WO2006065553
Kind Code:
A3
Abstract:
The present invention relates to vaccines for treating bacterial infections, which vaccines comprise a glycoconjugate immunogen comprising at least one capsular polysaccharide conjugated to a carrier protein, such that the capsular polysaccharide contains an amount of peptidoglycan effective to improve the vaccine's properties.
Inventors:
FATTOM ALI (US)
HAUSKNECHT ED (US)
WINSTON SCOTT (US)
FULLER STEVE (US)
HAUSKNECHT ED (US)
WINSTON SCOTT (US)
FULLER STEVE (US)
Application Number:
PCT/US2005/043593
Publication Date:
October 05, 2006
Filing Date:
December 02, 2005
Export Citation:
Assignee:
NABI BIOPHARMACEUTICALS (US)
FATTOM ALI (US)
HAUSKNECHT ED (US)
WINSTON SCOTT (US)
FULLER STEVE (US)
FATTOM ALI (US)
HAUSKNECHT ED (US)
WINSTON SCOTT (US)
FULLER STEVE (US)
International Classes:
A61K39/39; A61K39/085
Domestic Patent References:
| WO2003061558A2 | 2003-07-31 | |||
| WO2000056357A2 | 2000-09-28 |
Foreign References:
| EP0941736A1 | 1999-09-15 | |||
| US4094971A | 1978-06-13 |
Other References:
STEWART-TULL D E: "The immunological activities of bacterial peptidoglycans", ANNUAL REVIEW OF MICROBIOLOGY, ANNUAL REVIEWS INC., PALO ALTO, CA, US, vol. 34, 1980, pages 311 - 340, XP002106840, ISSN: 0066-4227
FATTOM A I ET AL: "Staphylococcus aureus vaccination for dialysis patients--an update", ADVANCES IN RENAL REPLACEMENT THERAPY, SAUNDERS, PHILADELPHIA, PA,, US, vol. 3, no. 4, October 1996 (1996-10-01), pages 302 - 308, XP009061936, ISSN: 1073-4449
FATTOM A I ET AL: "Staphylococcus aureus vaccination for dialysis patients--an update", ADVANCES IN RENAL REPLACEMENT THERAPY, SAUNDERS, PHILADELPHIA, PA,, US, vol. 3, no. 4, October 1996 (1996-10-01), pages 302 - 308, XP009061936, ISSN: 1073-4449
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