Title:
GPBP INHIBITORS AND USES AND SCALEABLE SYNTHESIS THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/134146
Kind Code:
A9
Abstract:
The present invention provides compounds and compositions thereof that inhibit Goodpasture antigen binding protein. Also disclosed is use of the compounds for the treatment various diseases and disorders, including invasive tumors, for the inhibition of mesenchymal phenotype after epithelial-to- mesenchymal transition (EMT), and for detecting EMT in a tissue. A method of preparing the compounds of the invention and related compounds is also provided.
Inventors:
SAUS JUAN (ES)
BLASCO RAUL (ES)
REVERT-ROS FRANCISCO (ES)
REVERT FERNANDO (ES)
RODA NURIA (ES)
BLASCO RAUL (ES)
REVERT-ROS FRANCISCO (ES)
REVERT FERNANDO (ES)
RODA NURIA (ES)
Application Number:
PCT/EP2017/052220
Publication Date:
June 20, 2019
Filing Date:
February 02, 2017
Export Citation:
Assignee:
FIBROSTATIN S L (ES)
SAUS JUAN (ES)
BLASCO RAUL (ES)
REVERT ROS FRANCISCO (ES)
REVERT FERNANDO (ES)
RODA NURIA (ES)
SAUS JUAN (ES)
BLASCO RAUL (ES)
REVERT ROS FRANCISCO (ES)
REVERT FERNANDO (ES)
RODA NURIA (ES)
International Classes:
C07D213/55; A61K31/44; A61P29/00; A61P37/00; C07C15/14; C07D213/57
Attorney, Agent or Firm:
ZWICKER, Jörk (DE)
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