Title:
GRAPE SKIN EXTRACT
Document Type and Number:
WIPO Patent Application WO/2020/246272
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a grape skin extract that exhibits a neurological function regulating action. The present invention is a grape skin extract that includes at least 15 mg/g malvidin-3,5-diglucoside in terms of dry weight.
Inventors:
ISODA HIROKO (JP)
SASAKI KAZUNORI (JP)
SATO KAZUHIKO (JP)
ASAKAWA MASUMI (JP)
TOMINAGA KENICHI (JP)
FUJISAWA HIROSHI (JP)
KOSHIYAMA MASAMI (JP)
SASAKI KAZUNORI (JP)
SATO KAZUHIKO (JP)
ASAKAWA MASUMI (JP)
TOMINAGA KENICHI (JP)
FUJISAWA HIROSHI (JP)
KOSHIYAMA MASAMI (JP)
Application Number:
PCT/JP2020/020360
Publication Date:
December 10, 2020
Filing Date:
May 22, 2020
Export Citation:
Assignee:
UNIV TSUKUBA (JP)
AIST (JP)
ZEON CORP (JP)
AIST (JP)
ZEON CORP (JP)
International Classes:
A61P25/16; A23L2/52; A23L33/105; A61K31/05; A61K31/7028; A61K36/87; A61P25/18; A61P25/24; A61P25/28; C12G1/00
Foreign References:
| CN104177460A | 2014-12-03 | |||
| JP2003277271A | 2003-10-02 | |||
| JP2007145825A | 2007-06-14 |
Other References:
OKAMOTO, G. ET AL.: "Juice constituents and skin pigments in Vitis coignetiae Pulliat grapevines", VITIS, vol. 41, no. 3, 2002, pages 161 - 162, XP055766431
CRUZ, A. ET AL.: "Anthocyanin Phytochemical Profiles and Anti-Oxidant Activities of Vitis Candicans and Vitis Doaniana", PHYTOCHEM ANAL., vol. 24, no. 5, 2013, pages 446 - 452, XP055766434
DREISEITEL, A. ET AL.: "Inhibition of Proteasome Activity by Anthocyanins and Anthocyanidins", BIOCHEM BIOPHYS RES COMMUN., vol. 372, no. 1, 2008, pages 57 - 61, XP022705342, DOI: 10.1016/j.bbrc.2008.04.140
DREISEITEL, A. ET AL.: "Berry Anthocyanins and Their Aglycons Inhibit Monoamine Oxidases A and B", PHARMACOL RES., vol. 59, 2009, pages 306 - 311, XP026063509, DOI: 10.1016/j.phrs.2009.01.014
TOMAZ, I.: "Solid-liquid Extraction of Phenolics From Red Grape Skins", ACTA CHIM SLOV., vol. 63, no. 2, 2016, pages 287 - 297, XP055767189
CRUZ, A. ET AL.: "Anthocyanin Identification and Composition of Wild Vitis Spp. Accessions by Using LC-MS and LC-NMR", ANAL CHIM ACTA., vol. 732, 2012, pages 145 - 152, XP028927934
MY. YOSHIDA ET AL.: "Anthocyanin suppresses the toxicity of Ap deposits through diversion of molecular forms in vitro and in vivo models of Alzheimer's disease", NUTRITIONAL NEUROSCIENCE, vol. 19, no. 1, 2016, pages 32 - 42, XP055712630, DOI: 10.1179/1476830515Y.0000000042
See also references of EP 3981471A4
CRUZ, A. ET AL.: "Anthocyanin Phytochemical Profiles and Anti-Oxidant Activities of Vitis Candicans and Vitis Doaniana", PHYTOCHEM ANAL., vol. 24, no. 5, 2013, pages 446 - 452, XP055766434
DREISEITEL, A. ET AL.: "Inhibition of Proteasome Activity by Anthocyanins and Anthocyanidins", BIOCHEM BIOPHYS RES COMMUN., vol. 372, no. 1, 2008, pages 57 - 61, XP022705342, DOI: 10.1016/j.bbrc.2008.04.140
DREISEITEL, A. ET AL.: "Berry Anthocyanins and Their Aglycons Inhibit Monoamine Oxidases A and B", PHARMACOL RES., vol. 59, 2009, pages 306 - 311, XP026063509, DOI: 10.1016/j.phrs.2009.01.014
TOMAZ, I.: "Solid-liquid Extraction of Phenolics From Red Grape Skins", ACTA CHIM SLOV., vol. 63, no. 2, 2016, pages 287 - 297, XP055767189
CRUZ, A. ET AL.: "Anthocyanin Identification and Composition of Wild Vitis Spp. Accessions by Using LC-MS and LC-NMR", ANAL CHIM ACTA., vol. 732, 2012, pages 145 - 152, XP028927934
MY. YOSHIDA ET AL.: "Anthocyanin suppresses the toxicity of Ap deposits through diversion of molecular forms in vitro and in vivo models of Alzheimer's disease", NUTRITIONAL NEUROSCIENCE, vol. 19, no. 1, 2016, pages 32 - 42, XP055712630, DOI: 10.1179/1476830515Y.0000000042
See also references of EP 3981471A4
Attorney, Agent or Firm:
SUGIMURA Kenji (JP)
Download PDF:
Previous Patent: NEUROLOGICAL FUNCTION REGULATING AGENT
Next Patent: EMULSIFIED HAIR-DRESSING COMPOSITION
Next Patent: EMULSIFIED HAIR-DRESSING COMPOSITION