Title:
GROUP OF GLYCOSYLTRANSFERASES AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2015/188742
Kind Code:
A2
Abstract:
The present invention relates to a group of glycosyltransferases and a use thereof. Specifically, the use of glycosyltransferase gGT29-7 and a polypeptide derived therefrom in catalytic glycosylation of a terpenoid and in synthesizing new saponins is provided. The glycosyltransferase is able to specifically and highly efficiently transfer a glycosyl from a glycosyl donor to a first glycosyl at the C-3 position and/or the C-6 position of a 4-ring triterpenoid, so as to extend the carbohydrate chain. The gylcosyltransferases of the present invention may also be used in constructing artificially synthesized ginsenosides and a variety of new ginsenosides and derivatives thereof.
Inventors:
ZHOU ZHIHUA (CN)
YAN XING (CN)
WANG PINGPING (CN)
WEI YONGJUN (CN)
WEI WEI (CN)
XU YUNPENG (CN)
LI XIAODONG (CN)
YANG CHENGSHUAI (CN)
YAN XING (CN)
WANG PINGPING (CN)
WEI YONGJUN (CN)
WEI WEI (CN)
XU YUNPENG (CN)
LI XIAODONG (CN)
YANG CHENGSHUAI (CN)
Application Number:
PCT/CN2015/081111
Publication Date:
December 17, 2015
Filing Date:
June 09, 2015
Export Citation:
Assignee:
SHANGHAI INST BIOL SCIENCES (CN)
International Classes:
C12P19/18; A01H4/00; C07K14/415; C12N9/10; C12N15/54; C12N15/63; C12P33/00
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
上海一平知识产权代理有限公司 (CN)
上海一平知识产权代理有限公司 (CN)
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