GSPT1 DEGRADERS, COMPOSITIONS COMPRISING THE DEGRADER, AND METHODS OF USING THE SAME

Title:

GSPT1 DEGRADERS, COMPOSITIONS COMPRISING THE DEGRADER, AND METHODS OF USING THE SAME

Document Type and Number:

WIPO Patent Application WO/2024/074127

Kind Code:

A1

Abstract:

Provided compounds of Formula (I), a tautomer thereof, a deuterated derivative of the compound or the tautomer, and a pharmaceutically acceptable salt of the foregoing, compositions comprising the compounds of Formula (I), a tautomer thereof, a deuterated derivative of the compound or the tautomer, and/or a pharmaceutically acceptable salt of the foregoing, and methods of using the same, in treating, for example, the diseases, disorders, or conditions mediated by the degradation of G1 to S phase transition protein 1 (GSPT1).

Inventors:

FANG LICHAO (CN)
LIU MIAO (CN)
MA TIANWEI (CN)

Application Number:

PCT/CN2023/123087

Publication Date:

April 11, 2024

Filing Date:

October 04, 2023

Export Citation:

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Assignee:

BIOFRONT LTD (KY)
FANG LICHAO (CN)

International Classes:

C07D401/14; A61K31/403; A61K31/44; A61P35/00; A61P35/02; C07D403/14

Attorney, Agent or Firm:

WU, FENG & ZHANG (CN)

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