GUANIDINE COMPOUND AND ASYMMETRIC REACTION USING THE SAME

WIPO Patent Application WO/2005/077908

A1

A guanidine compound which has a bi-aryl skeleton represented by the following general formula (1): [wherein R¹, R² and R³ each independently represents a hydrogen atom, a hydrocarbon group optionally having a substituent or a heterocyclic group optionally having a substituent, R⁴ to R¹⁵ each independently represents a hydrogen atom, a hydrocarbon group optionally having a substituent, a heterocyclic group optionally having a substituent, a hydroxyl group, an alkoxy group optionally having a substituent, an aryloxy group optionally having a substituent, an acyl group, an alkoxycarbonyl group optionally having a substituent, an aryloxycarbonyl group optionally having a substituent, a carbamoyl group optionally having a substituent, an alkylthiocarbonyl group optionally having a substituent, an arylthiocarbonyl group optionally having a substituent, a carboxyl group, an alkylthio group optionally having a substituent, an arylthio group optionally having a substituent, an amino group or a substututed amino group, or a substituted silyl group, and in any combination of R¹ to R¹⁵, these substituents may together bind with each other to form a ring, and X¹ to X⁸ each represents a carbon atom or a nitrogen atom, with the proviso that each of X¹ to X⁸ has no substituent when it is nitrogen]. The above guanidine compound is useful as a catalyst for a variety of asymmetric reactions.

TERADA MASAHIRO (JP)
UBE HITOSHI (JP)
YOKOYAMA SHIGEKO (JP)
SHIMIZU HIDEO (JP)

PCT/JP2005/001943

August 25, 2005

February 09, 2005

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TAKASAGO PERFUMERY CO LTD (JP)
TERADA MASAHIRO (JP)
UBE HITOSHI (JP)
YOKOYAMA SHIGEKO (JP)
SHIMIZU HIDEO (JP)

C07B53/00; C07B61/00; C07C201/12; C07C205/16; C07C205/40; C07D223/28; C07D245/04; C07D301/12; C07D301/14; C07D301/16; C07D301/19; C07D303/32; (IPC1-7): C07D223/28; C07D301/12; C07D301/14; C07D301/19; C07D303/32; C07B61/00; C07C201/12; C07C205/40; C07C205/16; C07M7/00

JP2000198774A	2000-07-18
JP2001048866A	2001-02-20
JPS61161266A	1986-07-21

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Iwatani, Ryo (1-31 Dojima 2-chome, Kita-k, Osaka-shi Osaka, JP)

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