Title:
HAEMATOPOIETIC-PROSTAGLANDIN D2 SYNTHASE INHIBITORS
Document Type and Number:
WIPO Patent Application WO/2011/150457
Kind Code:
A3
Abstract:
The present invention generally relates to compounds that inhibit haematopoietic-prostaglandin D2 synthase (H-PGDS), to compositions containing them and to their use in treating or preventing conditions and diseases associated with H-PGDS, such as allergies and inflammation.
Inventors:
SMYTHE MARK LESLIE (AU)
FLANAGAN JACK URQUHART (NZ)
FLANAGAN JACK URQUHART (NZ)
Application Number:
PCT/AU2011/000684
Publication Date:
January 26, 2012
Filing Date:
June 01, 2011
Export Citation:
Assignee:
UNIV QUEENSLAND (AU)
SMYTHE MARK LESLIE (AU)
FLANAGAN JACK URQUHART (NZ)
SMYTHE MARK LESLIE (AU)
FLANAGAN JACK URQUHART (NZ)
International Classes:
C07D333/02; A61K31/4436; A61K31/444; A61K31/5355; A61P1/00; A61P9/00; A61P11/08; A61P17/00; A61P19/02; A61P21/00; A61P35/00; A61P37/08
Domestic Patent References:
| WO2008121670A1 | 2008-10-09 | |||
| WO2007041634A1 | 2007-04-12 | |||
| WO2008078196A2 | 2008-07-03 | |||
| WO2007118137A1 | 2007-10-18 | |||
| WO2004006922A1 | 2004-01-22 | |||
| WO2010137738A1 | 2010-12-02 |
Other References:
PATANI, G.A. ET AL.: "Bioisosterism: A Rational Approach in Drug Design", CHEM. REV., vol. 96, 1996, pages 3147 - 3176, XP000652176, DOI: doi:10.1021/cr950066q
CHRIST, A. N. ET AL.: "Development and Characterization of New Inhibitors of the Human and Mouse Hematopoietic Prostaglandin D2 Synthases", JOURNAL OF MEDICINAL CHEMISTRY, vol. 53, no. 15, 2010, pages 5536 - 5548, XP055002058, DOI: doi:10.1021/jm100194a
See also references of EP 2576536A4
CHRIST, A. N. ET AL.: "Development and Characterization of New Inhibitors of the Human and Mouse Hematopoietic Prostaglandin D2 Synthases", JOURNAL OF MEDICINAL CHEMISTRY, vol. 53, no. 15, 2010, pages 5536 - 5548, XP055002058, DOI: doi:10.1021/jm100194a
See also references of EP 2576536A4
Attorney, Agent or Firm:
MORRIS, Kathryn B. et al. (Level 10301 Coronation Driv, Milton Queensland 4064, AU)
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