Title:
HAEMOCOAGULASE
Document Type and Number:
WIPO Patent Application WO/2008/046256
Kind Code:
A1
Abstract:
The present invention provides a haemocoagulase gene, its expressive functional
protein, and a hemostatic comprising the haemocoagulase. The haemocoagulase
gene of the present invention has the nucleotide sequence shown in SEQ ID NO: 1
or the gene sequence formed by the substitution, deletion or addition of one or
several nucleotides in SEQ ID NO: 1 and having the equivalent function as SEQ ID
NO: 1. The haemocoagulase has the amino acid sequence shown in SEQ ID NO: 2.
Inventors:
WANG XIJUAN (CN)
Application Number:
PCT/CN2006/003353
Publication Date:
April 24, 2008
Filing Date:
December 08, 2006
Export Citation:
Assignee:
HEALTHSTAR MEDICAL DEV CO LTD (CN)
WANG XIJUAN (CN)
WANG XIJUAN (CN)
International Classes:
C12N9/74; A61K38/48; A61P7/04; C12N15/57
Domestic Patent References:
| WO2005017139A1 | 2005-02-24 |
Foreign References:
| CN1534093A | 2004-10-06 |
Other References:
NOBUYUKI ITOH ET AL.: "Molecular Cloning and Sequence Analysis of cDNA for Batroxobin, a Thrombin-like Snake Venom Enzyme", J. BIOL. CHEM., vol. 262, no. 7, 5 March 1987 (1987-03-05), pages 3132 - 3135, XP002019838
NOBUYUKI ITOH ET AL.: "Organization of the Gene for Batroxobin, a Thrombin-like Snake Venom Enzyme", J. BIOL. CHEM., vol. 263, no. 16, 5 June 1988 (1988-06-05), pages 7628 - 7631
NOBUYUKI ITOH ET AL.: "The complete nucleotide sequence of the gene for batroxobin, a thrombin-like snake venom enzyme", NUCLEIC ACIDS RES., vol. 16, no. 21, 11 November 1988 (1988-11-11), pages 10377 - 10378
NOBUYUKI ITOH ET AL.: "Organization of the Gene for Batroxobin, a Thrombin-like Snake Venom Enzyme", J. BIOL. CHEM., vol. 263, no. 16, 5 June 1988 (1988-06-05), pages 7628 - 7631
NOBUYUKI ITOH ET AL.: "The complete nucleotide sequence of the gene for batroxobin, a thrombin-like snake venom enzyme", NUCLEIC ACIDS RES., vol. 16, no. 21, 11 November 1988 (1988-11-11), pages 10377 - 10378
Attorney, Agent or Firm:
CN-KNOWHOW INTELLECTUAL PROPERTY AGENT LIMITED (Fortune International CenterNo. 17 Daliushu Rd, Beijing 1, CN)
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