Title:
HALF IMMUNOGLOBULIN BINDING PROTEINS AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2012/088302
Kind Code:
A3
Abstract:
The invention provides compositions, methods, and kits related to half-Ig binding proteins that include a functional antibody binding site and a CH3 domain wherein the CH3 domain includes at least one mutation to inhibit CH3-CH3 dimerization.
Inventors:
GHAYUR TARIQ (US)
GU JIJIE (US)
LIU JUNJIAN (US)
HUTCHINS CHARLES W (US)
GU JIJIE (US)
LIU JUNJIAN (US)
HUTCHINS CHARLES W (US)
Application Number:
PCT/US2011/066557
Publication Date:
October 11, 2012
Filing Date:
December 21, 2011
Export Citation:
Assignee:
ABBOTT LAB (US)
GHAYUR TARIQ (US)
GU JIJIE (US)
LIU JUNJIAN (US)
HUTCHINS CHARLES W (US)
GHAYUR TARIQ (US)
GU JIJIE (US)
LIU JUNJIAN (US)
HUTCHINS CHARLES W (US)
International Classes:
A61K39/395; C12P21/08
Foreign References:
| US20100233079A1 | 2010-09-16 | |||
| US20100260668A1 | 2010-10-14 | |||
| US20100266531A1 | 2010-10-21 |
Other References:
AALBERSE ET AL.: "IgG4 breaking the rules", IMMUNOLOGY, vol. 105, 2002, pages 9 - 19, XP002987706
See also references of EP 2654792A4
See also references of EP 2654792A4
Attorney, Agent or Firm:
ZACHARAKIS, Maria Laccotripe et al. (LLP265 Franklin Stree, Boston MA, US)
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