HALOALKYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS

Title:

HALOALKYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS

Document Type and Number:

WIPO Patent Application WO/2010/056877

Kind Code:

A3

Abstract:

The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.

Inventors:

HART BARRY (US)
GREEN MICHAEL (US)
SETTI EDUARDO (US)
ROEPEL MICHAEL (US)

Application Number:

PCT/US2009/064227

Publication Date:

July 29, 2010

Filing Date:

November 12, 2009

Export Citation:

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Assignee:

VIROBAY INC (US)
HART BARRY (US)
GREEN MICHAEL (US)
SETTI EDUARDO (US)
ROEPEL MICHAEL (US)

International Classes:

C07C317/28; A61K31/277; A61P11/06; A61P19/02; C07C255/48

Domestic Patent References:

WO2008042968A2	2008-04-10
WO2006102535A2	2006-09-28
WO2006056047A1	2006-06-01
WO2006102423A1	2006-09-28

Other References: