Title:
HAPLOTYPES OF THE GSR GENE
Document Type and Number:
WIPO Patent Application WO2002042320
Kind Code:
A3
Abstract:
Novel genetic variants of the Glutathione Reductase (GSR) gene are described. Various genotypes, haplotypes, and haplotype pairs that exist in the general United States population are disclosed for the GSR gene. Compositions and methods for haplotyping and/or genotyping the GSR gene in an individual are also disclosed. Polynucleotides defined by the haplotypes disclosed herein are also described.
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Inventors:
BIEGLECKI KARYN M (US)
SANCHIS ANGELA (US)
SAUSKER ELIZABETH ANN (US)
SUN XIAO (US)
SANCHIS ANGELA (US)
SAUSKER ELIZABETH ANN (US)
SUN XIAO (US)
Application Number:
US0146473W
Publication Date:
December 31, 2003
Filing Date:
November 13, 2001
Export Citation:
Assignee:
GENAISSANCE PHARMACEUTICALS (US)
BIEGLECKI KARYN M (US)
SANCHIS ANGELA (US)
SAUSKER ELIZABETH ANN (US)
SUN XIAO (US)
BIEGLECKI KARYN M (US)
SANCHIS ANGELA (US)
SAUSKER ELIZABETH ANN (US)
SUN XIAO (US)
International Classes:
C12N9/02; (IPC1-7): C12Q1/68; C07H21/04; C12P19/34
Other References:
KELNER M.J. ET AL: "Structural Organization of the Human Glutathione Reductase Gene: Determination of Correct cDNA Sequence and Identification of a Mitochondrial Leader Sequence", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 269, 2000, pages 366 - 368, XP002959405
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