HAPLOTYPES OF THE IL5 GENE - GENAISSANCE PHARMACEUTICALS

Title:

HAPLOTYPES OF THE IL5 GENE

Document Type and Number:

WIPO Patent Application WO2001077132

Kind Code:

A3

Abstract:

Novel single nucleotide polymorphisms in the human Interleukin 5 (IL5) gene are described. In addition, various genotypes, haplotypes and haplotype pairs for the IL5 gene that exist in the population are described. Compositions and methods for haplotyping and/or genotyping the IL5 gene in an individual are also disclosed. Polynucleotides containing one or more of the IL5 polymorphisms disclosed herein are also described.

Inventors:

BENTIVEGNA STEVEN C (US)
CHEW ANNE (US)
CHOI JULIE Y (US)
DENTON R REX (US)
KAZEMI AMIR (US)
NANDABALAN KRISHNAN (US)
PARKS KATIE E (US)

Application Number:

PCT/US2001/012011

Publication Date:

February 28, 2002

Filing Date:

April 11, 2001

Export Citation:

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Assignee:

GENAISSANCE PHARMACEUTICALS (US)
BENTIVEGNA STEVEN C (US)
CHEW ANNE (US)
CHOI JULIE Y (US)
DENTON R REX (US)
KAZEMI AMIR (US)
NANDABALAN KRISHNAN (US)
PARKS KATIE E (US)

International Classes:

C12Q1/68; C12Q1/6876; G16B20/20; (IPC1-7): C12Q1/68

Other References:

CAMPBELL ET AL.: "Molecular cloning, nucleotide sequence and expression of the gene encoding human eosinophil differentiation factor (interleukin 5)", PROC. NATL. ACAD. SCI. USA, vol. 84, October 1987 (1987-10-01), pages 6629 - 6633, XP002949155
DATABASE GENEMBL [online] January 1998 (1998-01-01), CONNOLLY ET AL.: "Homo sapiens chromosome 5, PI clone 96c7", XP002949156, Database accession no. AC004042.1
SAMBROOK ET AL.: "Molecular cloning: A laboratory manual", 1989, COLD SPRING HARBOR LABORATORY PRESS, COLD SPRING HARBOR, XP002949157

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