Title:
HAPLOTYPES OF THE MMP13 GENE
Document Type and Number:
WIPO Patent Application WO2002006294
Kind Code:
A3
Abstract:
Novel genetic variants of the Matrix Metalloproteinase 13 (Collagenase 3) (MMP13) gene are described. Various genotypes, haplotypes, and haplotype pairs that exist in the general United States population are disclosed for the MMP13 gene. Compositions and methods for haplotyping and/or genotyping the MMP13 gene in an individual are also disclosed. Polynucleotides defined by the haplotypes disclosed herein are also described.
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Inventors:
FINKEL KEVIN (US)
KLIEM STEFANIE E (US)
MESSER CHAD (US)
TANGUAY DEBRA A (US)
KLIEM STEFANIE E (US)
MESSER CHAD (US)
TANGUAY DEBRA A (US)
Application Number:
PCT/US2001/022238
Publication Date:
May 02, 2002
Filing Date:
July 13, 2001
Export Citation:
Assignee:
GENAISSANCE PHARMACEUTICALS (US)
FINKEL KEVIN (US)
KLIEM STEFANIE E (US)
MESSER CHAD (US)
TANGUAY DEBRA A (US)
FINKEL KEVIN (US)
KLIEM STEFANIE E (US)
MESSER CHAD (US)
TANGUAY DEBRA A (US)
International Classes:
C12Q1/68; (IPC1-7): C12Q1/68; C07H21/04; C07K14/00; C07K16/00; C12P19/34
Other References:
FREIJE J.M.P. ET AL.: "Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 269, 1994, pages 16766 - 16773, XP002027323
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