Title:
HDAC INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/216298
Kind Code:
A1
Abstract:
Disclosed are a compound as shown in formula I, a stereoisomer thereof, and a pharmaceutically acceptable salt thereof. The present invention also relates to a pharmaceutical composition containing the compound of formula I and use of the compound in the preparation of HDAC inhibitor medicaments. The compound or the pharmaceutical composition thereof of the present invention can be used for treating cell proliferative diseases, autoimmune diseases, inflammation, neurodegenerative diseases or viral diseases.
Inventors:
LI JIN (CN)
ZHANG DENGYOU (CN)
CHU HONGZHU (CN)
LV KAIZHI (CN)
LIU LICHUAN (CN)
HU JING (CN)
HOU YANYAN (CN)
ZHANG DENGYOU (CN)
CHU HONGZHU (CN)
LV KAIZHI (CN)
LIU LICHUAN (CN)
HU JING (CN)
HOU YANYAN (CN)
Application Number:
PCT/CN2020/086427
Publication Date:
October 29, 2020
Filing Date:
April 23, 2020
Export Citation:
Assignee:
HITGEN INC (CN)
International Classes:
A61K31/416; C07D405/12; A61K31/423; A61K31/428; A61P25/28; A61P35/00; A61P37/00; C07D263/58; C07D277/68; C07D307/85; C07D333/70
Domestic Patent References:
| WO2019080882A1 | 2019-05-02 | |||
| WO2002030879A2 | 2002-04-18 |
Foreign References:
| CN101868446A | 2010-10-20 | |||
| CN107873023A | 2018-04-03 |
Other References:
YU, LIQIN ET AL.: "Pharmacophore Identification of Hydroxamate HDAC 1 Inhibitors", CHINESE JOURNAL OF CHEMISTRY, vol. 3, no. 27, 2 April 2009 (2009-04-02), XP002791263, DOI: 20200709105018
Attorney, Agent or Firm:
WAYNE INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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