HE4 DETECTING PEPTIDE AND USE THEREOF - UNIV AJOU IND ACADEMIC COOP FOUND

Title:

HE4 DETECTING PEPTIDE AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2023/195629

Kind Code:

A1

Abstract:

The present invention relates to a HE4 detecting peptide and use thereof and, more specifically, to a HE4 detecting peptide specifically binding to HE4 and use thereof for diagnosing ovarian cancer. The peptide specifically binding to HE4 according to the present invention can detect HE4 with high sensitivity and accuracy, and the peptide, when expressed on the bacteriophage coat and manufactured into a bacteriophage-based nano self-assembly, enables the convenient detection of HE4 from a sample through the observation of color changes by using a simple photographing device such as a smartphone, and especially, enables the detection of HE4 contained in a small amount in saliva, and thus can be very advantageously used in the early diagnosis of ovarian cancer.

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Inventors:

JIN HYO EON (KR)
SHIN DONGGUK (KR)

Application Number:

PCT/KR2023/002385

Publication Date:

October 12, 2023

Filing Date:

February 20, 2023

Export Citation:

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Assignee:

UNIV AJOU IND ACADEMIC COOP FOUND (KR)

International Classes:

C07K7/06; C12N7/00; C12Q1/6886; C12Q1/70; G01N21/78; G01N33/554; G01N33/574

Foreign References:

KR20200013118A	2020-02-05
KR20170100884A	2017-09-05
KR20160131172A	2016-11-16
KR20130065215A	2013-06-19
JP2009522578A	2009-06-11

Attorney, Agent or Firm:

ERUUM & LEEON INTELLECTUAL PROPERTY LAW FIRM (KR)

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