Title:
HEMOSTATIC MATERIAL AND WOUND DRESSING MATERIAL CONTAINING SAME
Document Type and Number:
WIPO Patent Application WO/2019/026177
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide: a hemostatic material which eliminates the risks characteristic of conventional chitosan-derived products such as endotoxin contamination and triggering of shellfish allergy, can be safely used on more people, and has antibiotic properties and hemostatic effects that widely-used hydrogels do not have; and a wound dressing material containing the same. Provided are a hemostatic agent containing a cationized cellulose and a wound dressing material containing the same. At least one hydroxyl group of the cationized cellulose is modified with -R2-N+(R3)(R4)(R5)·X-, and the other hydroxyl groups of the cationized cellulose have –H or -(CH2CH2O)m-H, where R2 is C1-6 alkylene, C2-6 hydroxyalkylene, -(CH2CH2O)l- or a combination thereof, and l is 1 or 2, m is 1 or 2, and X- may be an anionic group.
Inventors:
SHIBATA KAZUHIKO (JP)
Application Number:
PCT/JP2017/027890
Publication Date:
February 07, 2019
Filing Date:
August 01, 2017
Export Citation:
Assignee:
ARTISAN LAB CO LTD (JP)
NIPRO CORP (JP)
NIPRO CORP (JP)
International Classes:
A61L15/28
Foreign References:
| JPS63152601A | 1988-06-25 | |||
| JP2002512087A | 2002-04-23 | |||
| JP2011507860A | 2011-03-10 | |||
| JP2015537004A | 2015-12-24 | |||
| JPS62183768A | 1987-08-12 | |||
| CN103724568A | 2014-04-16 | |||
| CN104162184A | 2014-11-26 | |||
| JPS50150296A | 1975-12-02 | |||
| US4921691A | 1990-05-01 | |||
| JP2017140231A | 2017-08-17 | |||
| JP2011518592A | 2010-06-11 | |||
| JP2013133287A | 2013-07-08 |
Other References:
ANONYMOUS: "Poizu C-60H, Kao Chemical Seihin, Kao Chemicals", POIZU C-60H, KAO CHEMICAL SEIHIN, KAO CHEMICALS, 2010, pages 1 - 5, XP009518558, Retrieved from the Internet [retrieved on 20171004]
GEORGIA A. KANNONALGIN B. GARRETT: "Moist Wound Healing with Occlusive Dressings", DERMATOLOGIC SURGERY, vol. 21, no. 7, July 1995 (1995-07-01), pages 583 - 590
REJANE C. GOYDOUGLAS DE BRITTOODILIO B. G. ASSIS: "A review of the antibacterial activity of chitosan", POLIMEROS, vol. 19, no. 3, 2009, pages 241 - 247
TSUIMIN TSAIHSIUNG-FEICHIEN: "Chitosan Augments Photodynamic Inactivation of Gram-Positive and Gram-Negative Bacteria", ANTIMICROBIAL AGENTS CHEMOTHERAPY, vol. 5, no. 5, 5 May 2011 (2011-05-05), pages 1883 - 1890
SYOTA SUZUKIKAZUHIKO SHIBATA: "Randomized Trial comparing New Chitosan-Based Bandage with Kaltostat Hemostatic Dressing to Control Bleeding from Hemodialysis Puncture Site", NEPHROL. DIAL. TRANSPLANT., vol. 28, no. 1, 2013, pages i226 - i239
See also references of EP 3662937A4
GEORGIA A. KANNONALGIN B. GARRETT: "Moist Wound Healing with Occlusive Dressings", DERMATOLOGIC SURGERY, vol. 21, no. 7, July 1995 (1995-07-01), pages 583 - 590
REJANE C. GOYDOUGLAS DE BRITTOODILIO B. G. ASSIS: "A review of the antibacterial activity of chitosan", POLIMEROS, vol. 19, no. 3, 2009, pages 241 - 247
TSUIMIN TSAIHSIUNG-FEICHIEN: "Chitosan Augments Photodynamic Inactivation of Gram-Positive and Gram-Negative Bacteria", ANTIMICROBIAL AGENTS CHEMOTHERAPY, vol. 5, no. 5, 5 May 2011 (2011-05-05), pages 1883 - 1890
SYOTA SUZUKIKAZUHIKO SHIBATA: "Randomized Trial comparing New Chitosan-Based Bandage with Kaltostat Hemostatic Dressing to Control Bleeding from Hemodialysis Puncture Site", NEPHROL. DIAL. TRANSPLANT., vol. 28, no. 1, 2013, pages i226 - i239
See also references of EP 3662937A4
Attorney, Agent or Firm:
FUJITA, Takaharu (JP)
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