Title:
HER-2-SPECIFIC CYCLIZED SUPR PEPTIDES
Document Type and Number:
WIPO Patent Application WO/2017/078761
Kind Code:
A3
Abstract:
Disclosed are highly potent peptides, peptide conjugates, host cells and compositions containing one or more of these peptides, peptide conjugates and/or host cells that are useful to inhibit the growth of a breast cancer cell or treat breast cancer in a patient in need of such treatment.
Inventors:
FIACCO STEPHEN (US)
HARDY AMANDA (US)
HARDY AMANDA (US)
Application Number:
PCT/US2016/000107
Publication Date:
August 10, 2017
Filing Date:
November 07, 2016
Export Citation:
Assignee:
EVORX TECH INC (US)
FIACCO STEPHEN (US)
HARDY AMANDA (US)
FIACCO STEPHEN (US)
HARDY AMANDA (US)
International Classes:
C07K7/06; A61K38/00; A61K49/00; A61K51/08; C07K7/64
Foreign References:
| US20150050211A1 | 2015-02-19 | |||
| US20140010831A1 | 2014-01-09 | |||
| US20080081768A1 | 2008-04-03 | |||
| US6025140A | 2000-02-15 |
Other References:
MILLWARD ET AL.: "Design of cyclic peptides that bind protein surfaces with antibody-like affinity", ACS CHEMICAL BIOLOGY, vol. 2, no. 9, 2007, pages 625 - 634, XP002616292
FIACCO ET AL.: "Directed evolution of scanning unnatural-protease-resistant (SUPR) peptides for in vivo applications", CHEMBIOCHEM, vol. 17, 2 September 2016 (2016-09-02), pages 1643 - 1651, XP002772939
FIACCO ET AL.: "Directed evolution of scanning unnatural-protease-resistant (SUPR) peptides for in vivo applications", CHEMBIOCHEM, vol. 17, 2 September 2016 (2016-09-02), pages 1643 - 1651, XP002772939
Attorney, Agent or Firm:
GARVEY, John, M. et al. (US)
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