Title:
HERPES ZOSTER VACCINE COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2023/116374
Kind Code:
A1
Abstract:
Provided is a herpes zoster vaccine composition. The composition comprises a varicella-zoster virus antigen and a composite adjuvant, wherein the composite adjuvant comprises a CpG oligodeoxynucleotide, QS-21 and a liposome, and the CpG oligodeoxynucleotide is CpG 7909. The composition can induce a strong antibody reaction and T cell immune response, and is used for preventing varicella-zoster virus infections.
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Inventors:
ZHANG CHAO (CN)
LU YANG (CN)
ZHU QIANJUN (CN)
ZHANG LINGLI (CN)
YANG YUNQI (CN)
GUO HUILI (CN)
WANG ZIYAN (CN)
HU DONGDONG (CN)
QIAN DAWEI (CN)
LIU HAIPING (CN)
DIAO MEIJUN (CN)
SHEN QIAOYING (CN)
ZHOU CHENLIANG (CN)
LIU GE (CN)
LU YANG (CN)
ZHU QIANJUN (CN)
ZHANG LINGLI (CN)
YANG YUNQI (CN)
GUO HUILI (CN)
WANG ZIYAN (CN)
HU DONGDONG (CN)
QIAN DAWEI (CN)
LIU HAIPING (CN)
DIAO MEIJUN (CN)
SHEN QIAOYING (CN)
ZHOU CHENLIANG (CN)
LIU GE (CN)
Application Number:
PCT/CN2022/135376
Publication Date:
June 29, 2023
Filing Date:
November 30, 2022
Export Citation:
Assignee:
SHANGHAI ZERUN BIOTECHNOLOGY CO LTD (CN)
International Classes:
A61K39/25; A61K45/00
Foreign References:
| US20070212328A1 | 2007-09-13 | |||
| CN112972671A | 2021-06-18 | |||
| CN112972670A | 2021-06-18 | |||
| US20180021424A1 | 2018-01-25 | |||
| US20070298093A1 | 2007-12-27 |
Other References:
GUO SHUYANG, LI MIN : "The CMC Consideration of Novel Adjuvant Vaccines", CHINESE JOURNAL OF NEW DRUGS, vol. 29, no. 17, 15 September 2020 (2020-09-15), CN , pages 1939 - 1941, XP093074327, ISSN: 1003-3734
Attorney, Agent or Firm:
CHINA PATENT AGENT (HK) LTD. (CN)
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