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Title:
HETEROARYL AMIDE COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITIONS THEREOF, AND APPLICATIONS THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/085978
Kind Code:
A1
Abstract:
The present invention relates to heteroaryl amide compounds, a preparation method therefor, pharmaceutical compositions thereof and applications thereof, and specifically, relates to a type of compounds having broad-spectrum tumor resistant activity, a preparation method therefor, pharmaceutical compositions containing the compounds, and uses of the compounds in the preparation of drugs for treating tumors.

Inventors:
REN, Ruibao (197 Rui Jin Road Ii, Huang Pu District, Shanghai 5, 200025, CN)
DENG, Xianming (No. 422 Si Ming Nan Road, Siming DistrictXiamen, Fujian 5, 361005, CN)
WU, Min (197 Rui Jin Road Ii, Huang Pu District, Shanghai 5, 200025, CN)
ZHANG, Ting (No. 422 Si Ming Nan Road, Siming DistrictXiamen, Fujian 5, 361005, CN)
JIAO, Bo (197 Rui Jin Road Ii, Huang Pu District, Shanghai 5, 200025, CN)
KANG, Qiaofeng (No. 422 Si Ming Nan Road, Siming DistrictXiamen, Fujian 5, 361005, CN)
HUANG, Wei (No. 422 Si Ming Nan Road, Siming DistrictXiamen, Fujian 5, 361005, CN)
Application Number:
CN2018/113549
Publication Date:
May 09, 2019
Filing Date:
November 02, 2018
Export Citation:
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Assignee:
RUI JIN HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE (197 Rui Jin Road Ii, Huang Pu District, Shanghai 5, 200025, CN)
XIAMEN UNIVERSITY (No. 422 Si Ming Nan Road, Siming DistrictXiamen, Fujian 5, 361005, CN)
International Classes:
C07D513/04; A61K31/425; A61P35/00
Foreign References:
CN101790313A2010-07-28
Other References:
SARTORI, LUCA ET AL.: "Thieno[3, 2-b]pyrrole-5-carboxamides as New Rever- sible Inhibitors of Histone Lysine Demethylase KDMIA/LSDI.Part 1.High-Throu- ghput Screening and reliminary Exploration", JOURNAL OF MEDICINAL CHEMISTRY, vol. 60, no. 5, 10 February 2017 (2017-02-10), pages 1673 - 1692, XP055507204
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (8th Floor, Vantone New World Plaza2 Fuchengmenwai Street, Xicheng District, Beijing 7, 100037, CN)
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