Title:
HETEROBICYCLIC CARBOXYLIC ACIDS AND SALTS THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/166022
Kind Code:
A1
Abstract:
The present invention provides pharmaceutically acceptable salts of compounds of Formula I that are potent EP4 receptor antagonists and can be used for treating cancer or inflammatory diseases alone or in combination with antibody therapy, radiation therapy, anti‐metabolite chemotherapy to a subject in need thereof.
Inventors:
ZHOU GANG (US)
SUN YONGKUI (CN)
WANG ZHAOYIN (CA)
SUN YONGKUI (CN)
WANG ZHAOYIN (CA)
Application Number:
PCT/CN2019/076882
Publication Date:
September 06, 2019
Filing Date:
March 04, 2019
Export Citation:
Assignee:
SHENZHEN IONOVA LIFE SCIENCE CO LTD (CN)
FOSHAN IONOVA BIOTHERAPEUTICS CO LTD (CN)
FOSHAN IONOVA BIOTHERAPEUTICS CO LTD (CN)
International Classes:
C07D495/04; A61K31/407; A61P29/00; A61P35/00
Domestic Patent References:
| WO2010121382A1 | 2010-10-28 | |||
| WO2010019796A1 | 2010-02-18 | |||
| WO2007121578A1 | 2007-11-01 | |||
| WO2007143825A1 | 2007-12-21 | |||
| WO2017066633A1 | 2017-04-20 | |||
| WO2008052898A1 | 2008-05-08 |
Other References:
See also references of EP 3759114A4
Attorney, Agent or Firm:
BEIJING CELUE LAW FIRM (CN)
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