Title:
HETEROCYCLIC AMIDE DERIVATIVE, AND MEDICINE CONTAINING SAME
Document Type and Number:
WIPO Patent Application WO/2014/098098
Kind Code:
A1
Abstract:
A compound represented by formula (I) [wherein each symbol is as defined in the description] has a TRPA1 antagonistic activity, and the compound and a medicine containing the compound are useful for the prevention or treatment of diseases associated with a TRPA1 antagonist and TRPA1.
Inventors:
KOBAYASHI KAORI (JP)
SUZUKI TAMOTSU (JP)
OKUZUMI TATSUYA (JP)
SUZUKI TAMOTSU (JP)
OKUZUMI TATSUYA (JP)
Application Number:
PCT/JP2013/083801
Publication Date:
June 26, 2014
Filing Date:
December 17, 2013
Export Citation:
Assignee:
AJINOMOTO KK (JP)
International Classes:
C07D205/04; A61K31/397; A61K31/401; A61K31/4025; A61K31/427; A61K31/4439; A61K31/4709; A61K31/4725; A61K31/5377; A61P1/00; A61P1/04; A61P1/08; A61P11/00; A61P11/06; A61P13/10; A61P17/00; A61P17/04; A61P25/00; A61P25/04; A61P29/00; A61P43/00; C07D207/16; C07D207/22; C07D409/12; C07D409/14; C07D413/12; C07D417/14; C12N15/00; C12N15/09
Domestic Patent References:
| WO2012152983A1 | 2012-11-15 | |||
| WO2010141805A1 | 2010-12-09 | |||
| WO2013108857A1 | 2013-07-25 | |||
| WO2010141805A1 | 2010-12-09 |
Foreign References:
| JP2001524465A | 2001-12-04 | |||
| US6645939B1 | 2003-11-11 |
Other References:
DATABASE REGISTRY [online] 15 April 2010 (2010-04-15), XP055263661, retrieved from STN Database accession no. 1219351-47-9
DATABASE REGISTRY [online] 26 August 2009 (2009-08-26), XP055263624, retrieved from STN Database accession no. 1175811-39-8
DATABASE REGISTRY [online] 25 August 2009 (2009-08-25), XP055263663, retrieved from STN Database accession no. 1175637-16-7
BANDELL M ET AL., NEURON, vol. 41, no. 6, 25 March 2004 (2004-03-25), pages 849 - 57
MACPHERSON LJ ET AL., NATURE, vol. 445, no. 7127, 2007, pages 541 - 5
TREVISANI M ET AL., PROC NATL ACAD SCI U S A., vol. 104, no. 33, 2007, pages 13519 - 24
ZURBORG S ET AL., NAT NEUROSCI., vol. 10, no. 3, 2007, pages 277 - 9
NAGATA K ET AL., J NEUROSCI., vol. 25, no. 16, 2005, pages 4052 - 61
STORY GM ET AL., CELL, vol. 112, no. 6, 2003, pages 819 - 29
BAUTISTA DM ET AL., PROC NATL ACAD SCI U S A., vol. 102, no. 34, 2005, pages 12248 - 52
OBATA K ET AL., J CLIN INVEST., vol. 115, no. 9, 2005, pages 2393 - 401
MCNAMARA CR ET AL., PROC NATL ACAD SCI U S A., vol. 104, no. 33, 2007, pages 13525 - 30
KONDO T ET AL., DIGESTION, vol. 82, no. 3, 2010, pages 150 - 5
CATTARUZZA F ET AL., AM J PHYSIOL GASTROINTEST LIVER PHYSIOL., vol. 298, no. 1, 2010, pages G81 - 91
CACERES AI ET AL., PROC NATL ACAD SCI U S A., vol. 106, no. 22, 2009, pages 9099 - 104
XIAO B; PATAPOUTIAN A., NAT NEUROSCI., vol. 14, no. 5, May 2011 (2011-05-01), pages 540 - 2
WILSON SR ET AL., NAT NEUROSCI., vol. 14, no. 5, May 2011 (2011-05-01), pages 595 - 602
MCGARAUGHTY S ET AL., MOL PAIN., vol. 6, 5 March 2010 (2010-03-05), pages 14
ANDERSSON KE ET AL., BJU INT., vol. 106, no. 8, October 2010 (2010-10-01), pages 1114 - 27
NASSINI R ET AL., PAIN, vol. 152, no. 7, July 2011 (2011-07-01), pages 1621 - 31
DATABASE REGISTRY [online] 26 August 2009 (2009-08-26), XP055263624, retrieved from STN Database accession no. 1175811-39-8
DATABASE REGISTRY [online] 25 August 2009 (2009-08-25), XP055263663, retrieved from STN Database accession no. 1175637-16-7
BANDELL M ET AL., NEURON, vol. 41, no. 6, 25 March 2004 (2004-03-25), pages 849 - 57
MACPHERSON LJ ET AL., NATURE, vol. 445, no. 7127, 2007, pages 541 - 5
TREVISANI M ET AL., PROC NATL ACAD SCI U S A., vol. 104, no. 33, 2007, pages 13519 - 24
ZURBORG S ET AL., NAT NEUROSCI., vol. 10, no. 3, 2007, pages 277 - 9
NAGATA K ET AL., J NEUROSCI., vol. 25, no. 16, 2005, pages 4052 - 61
STORY GM ET AL., CELL, vol. 112, no. 6, 2003, pages 819 - 29
BAUTISTA DM ET AL., PROC NATL ACAD SCI U S A., vol. 102, no. 34, 2005, pages 12248 - 52
OBATA K ET AL., J CLIN INVEST., vol. 115, no. 9, 2005, pages 2393 - 401
MCNAMARA CR ET AL., PROC NATL ACAD SCI U S A., vol. 104, no. 33, 2007, pages 13525 - 30
KONDO T ET AL., DIGESTION, vol. 82, no. 3, 2010, pages 150 - 5
CATTARUZZA F ET AL., AM J PHYSIOL GASTROINTEST LIVER PHYSIOL., vol. 298, no. 1, 2010, pages G81 - 91
CACERES AI ET AL., PROC NATL ACAD SCI U S A., vol. 106, no. 22, 2009, pages 9099 - 104
XIAO B; PATAPOUTIAN A., NAT NEUROSCI., vol. 14, no. 5, May 2011 (2011-05-01), pages 540 - 2
WILSON SR ET AL., NAT NEUROSCI., vol. 14, no. 5, May 2011 (2011-05-01), pages 595 - 602
MCGARAUGHTY S ET AL., MOL PAIN., vol. 6, 5 March 2010 (2010-03-05), pages 14
ANDERSSON KE ET AL., BJU INT., vol. 106, no. 8, October 2010 (2010-10-01), pages 1114 - 27
NASSINI R ET AL., PAIN, vol. 152, no. 7, July 2011 (2011-07-01), pages 1621 - 31
Attorney, Agent or Firm:
TAKASHIMA, HAJIME (JP)
Takashima 1 (JP)
Takashima 1 (JP)
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