Title:
HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/046409
Kind Code:
A1
Abstract:
The present invention relates to a heterocyclic compound, a preparation method therefor, and a pharmaceutical use thereof. Specifically, the present invention relates to a heterocyclic compound as shown in general formula (I), a preparation method therefor, a pharmaceutical composition containing the compound, and a use of the heterocyclic compound as a therapeutic agent, especially a use as a Nav inhibitor and a use in preparation of drugs for treating and/or alleviating pain and pain-related diseases. The groups in general formula (I) are as defined in the description.
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Inventors:
LI XIN (CN)
CAI GUODONG (CN)
CHEN YANG (CN)
WANG BIN (CN)
HE FENG (CN)
CAI GUODONG (CN)
CHEN YANG (CN)
WANG BIN (CN)
HE FENG (CN)
Application Number:
PCT/CN2023/116053
Publication Date:
March 07, 2024
Filing Date:
August 31, 2023
Export Citation:
Assignee:
JIANGSU HENGRUI PHARMACEUTICALS CO LTD (CN)
SHANGHAI HENGRUI PHARMACEUTICAL CO LTD (CN)
SHANGHAI HENGRUI PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D409/12; A61K31/443; A61P29/00; C07D405/12; C07D405/14; C07D407/14; C07D413/14; C07D417/12; C07D471/04; C07D471/08; C07D487/08; C07D491/052; C07D491/08; C07D491/10; C07D498/04; C07D521/00
Domestic Patent References:
| WO2022256702A1 | 2022-12-08 | |||
| WO2022256679A1 | 2022-12-08 |
Foreign References:
| US20180289706A1 | 2018-10-11 | |||
| CN108349968A | 2018-07-31 | |||
| CN102241621A | 2011-11-16 | |||
| CN114945566A | 2022-08-26 | |||
| CN111065383A | 2020-04-24 | |||
| US5491152A | 1996-02-13 |
Attorney, Agent or Firm:
GE CHENG & CO., LTD (CN)
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