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Title:
HETEROCYCLIC COMPOUND
Document Type and Number:
WIPO Patent Application WO/2020/122092
Kind Code:
A1
Abstract:
The present invention provides a heterocyclic compound having orexin receptor type 2 agonist activity. A compound represented by formula (I) [in the formula, each symbol is as described in the description] or a salt thereof has orexin receptor type 2 agonist activity and is useful as a prophylactic or therapeutic agent for narcolepsy.

Inventors:
MIYANOHANA YUHEI (JP)
KAJITA YUICHI (JP)
KOIKE TATSUKI (JP)
HOASHI YASUTAKA (JP)
HATTORI YASUSHI (JP)
TOKUNAGA NORIHITO (JP)
ODA TSUNEO (JP)
MIYAZAKI TOHRU (JP)
AINIWAER DILIHUMAER (JP)
ITO YOSHITERU (JP)
TAKEUCHI KOHEI (JP)
IMAMURA KEISUKE (JP)
SUGIMOTO TAKAHIRO (JP)
FUKUDA KOICHIRO (JP)
KOHARA YASUHISA (JP)
OKAMOTO REI (JP)
OHRA TAIICHI (JP)
MIYAMOTO NAOKI (JP)
CHIBA JUN (JP)
TERAO YOSHITO (JP)
KAWASAKI MASANORI (JP)
Application Number:
JP2019/048384
Publication Date:
June 18, 2020
Filing Date:
December 11, 2019
Export Citation:
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Assignee:
TAKEDA PHARMACEUTICALS CO (JP)
International Classes:
A61K31/437; A61K31/4375; A61K31/444; A61K31/472; A61K31/4985; A61K31/502; A61K31/517; A61K31/519; A61K31/5383; A61P25/26; A61P43/00; C07D217/24; C07D237/28; C07D237/32; C07D239/90; C07D401/10; C07D403/10; C07D405/10; C07D417/10; C07D455/02; C07D471/04; C07D498/04
Domestic Patent References:
WO2017135306A12017-08-10
Foreign References:
JP2005532381A2005-10-27
Other References:
YUKARI MIZUNO, TOMOKO TSUJITANI, YASUNORI HAMAUZU: "Characteristics and Food Function of Cell Wall Components in Some Fruits", ENGEIGAKU KENKYUU, 1 January 2010 (2010-01-01), pages 113 - 120, XP055720100, Retrieved from the Internet DOI: 10.2503/hrj.9.113
JANA JANOCKOVA, ET AL: "Investigation of New Orexin 2 Receptor Modulators Using In Silico and In Vitro Methods", MOLECULES, vol. 23, no. 11, 1 January 2018 (2018-01-01), pages 2926, XP055720169, DOI: 10.3390/molecules23112926
Attorney, Agent or Firm:
TAKASHIMA, Hajime (JP)
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