Title:
HETEROCYCLIC COMPOUNDS FOR AGING-RELATED AND DIABETIC VASCULAR COMPLICATIONS
Document Type and Number:
WIPO Patent Application WO2002085897
Kind Code:
A9
Abstract:
The invention discloses a new clause of a five membered heterocyclic ring compounds of general formula (1) and its pharmaceutically or cosmetically acceptable salts, wherein R1, R2, R3, R4, R5, A, B, X and Y are as defined in the specification. The invention also discloses a process for preparation of these compound and their therapeutic and cosmetic applications particularly in the managemnt of agin related and diabetic vascular complications. The compounds in question act by triple action of an AGE (Advanced Glycation Endproducts) breaker, AGE inhibitor and free radical scavenger which make them most suitable in different therapeutic and cosmetic applications. The invention also discloses pharmaceuticals and cosmetic compositions comprisisng these compounds and method of treatment of diseases caused by accumulation of AGE and/or free radicals in the body cells.
Inventors:
SANKARANARAYANAN ALANGUDI (IN)
Application Number:
PCT/IB2002/001137
Publication Date:
April 01, 2004
Filing Date:
April 02, 2002
Export Citation:
Assignee:
SANKARANARAYANAN ALANGUDI (IN)
International Classes:
A61K8/00; A61K8/49; A61K31/4427; A61K31/4436; C07D401/04; A61K31/4439; A61K31/4545; A61K31/4709; A61P1/00; A61P1/16; A61P3/00; A61P9/10; A61P11/00; A61P13/12; A61P15/10; A61P25/00; A61P25/28; A61P27/02; A61P29/00; A61P31/18; A61P35/00; A61P37/02; A61P39/06; A61P43/00; A61Q17/04; A61Q19/00; A61Q19/08; C07D401/14; C07D409/00; C07D409/04; C07D409/14; C07D411/04; C07D413/04; C07D413/14; (IPC1-7): C07D409/14; C07D413/14; A61K31/4439; A61P3/10
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