Title:
HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
Document Type and Number:
WIPO Patent Application WO/2023/179703
Kind Code:
A1
Abstract:
Provided herein are compounds having the following structure (I), wherein the substituents are as defined herein, compositions comprising an effective amount of a compound, and methods for modulating activity of KRAS G12D and/or G12V.
Inventors:
YU CHAO (CN)
CHEN JIE (CN)
SUN HANZI (CN)
LIU HUAQING (CN)
WANG CE (CN)
WANG ZHIWEI (CN)
CHEN JIE (CN)
SUN HANZI (CN)
LIU HUAQING (CN)
WANG CE (CN)
WANG ZHIWEI (CN)
Application Number:
PCT/CN2023/083294
Publication Date:
September 28, 2023
Filing Date:
March 23, 2023
Export Citation:
Assignee:
BEIGENE LTD (GB)
YU CHAO (CN)
YU CHAO (CN)
International Classes:
C07D471/14; A61K31/517; A61P35/00
Domestic Patent References:
| WO2022031678A1 | 2022-02-10 | |||
| WO2022132200A1 | 2022-06-23 | |||
| WO2022214102A1 | 2022-10-13 | |||
| WO2022247760A1 | 2022-12-01 | |||
| WO2022248885A2 | 2022-12-01 | |||
| WO2023020518A1 | 2023-02-23 | |||
| WO2023020521A1 | 2023-02-23 | |||
| WO2022177917A2 | 2022-08-25 | |||
| WO2023004102A2 | 2023-01-26 | |||
| WO2023056951A1 | 2023-04-13 | |||
| WO2023061294A1 | 2023-04-20 | |||
| WO2023081840A1 | 2023-05-11 | |||
| WO2023072188A1 | 2023-05-04 |
Foreign References:
| CN115304623A | 2022-11-08 |
Attorney, Agent or Firm:
WU , FENG & ZHANG (CN)
Download PDF: