Title:
HETEROCYCLIC INDANONE POTENTIATORS OF METABOTROPIC GLUTAMATE RECEPTORS
Document Type and Number:
WIPO Patent Application WO2006047237
Kind Code:
A3
Abstract:
The present invention is directed to compounds which are potentiators of metabotropic glutamate receptors, including the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved.
Inventors:
PINKERTON ANTHONY B (US)
VERNIER JEAN-MICHEL (US)
CUBE ROWENA V (US)
HUTCHINSON JOHN H (US)
VERNIER JEAN-MICHEL (US)
CUBE ROWENA V (US)
HUTCHINSON JOHN H (US)
Application Number:
PCT/US2005/037797
Publication Date:
November 02, 2006
Filing Date:
October 21, 2005
Export Citation:
Assignee:
MERCK & CO INC (US)
PINKERTON ANTHONY B (US)
VERNIER JEAN-MICHEL (US)
CUBE ROWENA V (US)
HUTCHINSON JOHN H (US)
PINKERTON ANTHONY B (US)
VERNIER JEAN-MICHEL (US)
CUBE ROWENA V (US)
HUTCHINSON JOHN H (US)
International Classes:
A61K31/4192; A61K31/4164; A61K31/44; C07D213/70
Foreign References:
| US4983628A | 1991-01-08 |
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