Title:
HEXAMERIC N-FORMYL PEPTIDE LIBRARY AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/128507
Kind Code:
A1
Abstract:
The present invention provides a hexameric N-formyl peptide library and uses thereof, wherein the hexameric N-formyl peptide library is for discovering a formyl-peptide receptor activating active substance for the development of a therapeutic agent for inflammatory diseases using a synthetic peptide with increased affinity to a specific receptor.
Inventors:
LEE TAE HOON (KR)
GHIM JAEWANG (KR)
KIM YOUNG EUN (KR)
CHANG YEONHO (KR)
JEONG MIN GYU (KR)
GHIM JAEWANG (KR)
KIM YOUNG EUN (KR)
CHANG YEONHO (KR)
JEONG MIN GYU (KR)
Application Number:
PCT/KR2022/021294
Publication Date:
July 06, 2023
Filing Date:
December 26, 2022
Export Citation:
Assignee:
NOVACELL TECH INC (KR)
International Classes:
C07K1/04; C07K7/06; C07K14/00; C40B40/10; G01N33/50; G01N33/68
Foreign References:
| US20030055001A1 | 2003-03-20 | |||
| US5925529A | 1999-07-20 |
Other References:
RAABE CARSTEN ALEXANDER; GROPER JIENY; RESCHER URSULA: "Biased perspectives on formyl peptide receptors", BIOCHIMICA ET BIOPHYSICA ACTA, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM., NL, vol. 1866, no. 2, 1 January 1900 (1900-01-01), NL , pages 305 - 316, XP085569326, ISSN: 0167-4889, DOI: 10.1016/j.bbamcr.2018.11.015
HE HUI-QIONG, YE RICHARD: "The Formyl Peptide Receptors: Diversity of Ligands and Mechanism for Recognition", MOLECULES, vol. 22, no. 3, pages 455, XP093073981, DOI: 10.3390/molecules22030455
J. JACOB STROUSE; SUSAN M. YOUNG; HUGH D. MITCHELL; RICHARD D. YE; ERIC R. PROSSNITZ; LARRY A. SKLAR; BRUCE S. EDWARDS: "A novel fluorescent cross‐reactive formylpeptide receptor/formylpeptide receptor‐like 1 hexapeptide ligand", CYTOMETRY A, WILEY-LISS, HOBOKEN, USA, no. 3, 11 November 2008 (2008-11-11), Hoboken, USA, pages 264 - 270, XP072332109, ISSN: 1552-4922, DOI: 10.1002/cyto.a.20670
HE HUI-QIONG, YE RICHARD: "The Formyl Peptide Receptors: Diversity of Ligands and Mechanism for Recognition", MOLECULES, vol. 22, no. 3, pages 455, XP093073981, DOI: 10.3390/molecules22030455
J. JACOB STROUSE; SUSAN M. YOUNG; HUGH D. MITCHELL; RICHARD D. YE; ERIC R. PROSSNITZ; LARRY A. SKLAR; BRUCE S. EDWARDS: "A novel fluorescent cross‐reactive formylpeptide receptor/formylpeptide receptor‐like 1 hexapeptide ligand", CYTOMETRY A, WILEY-LISS, HOBOKEN, USA, no. 3, 11 November 2008 (2008-11-11), Hoboken, USA, pages 264 - 270, XP072332109, ISSN: 1552-4922, DOI: 10.1002/cyto.a.20670
Attorney, Agent or Firm:
HAN, Yun Ho (KR)
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