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Title:
HGF PRODUCTION ACCELERATOR CONTAINING HEPARIN-LIKE OLIGOSACCHARIDE
Document Type and Number:
WIPO Patent Application WO/2005/092348
Kind Code:
A1
Abstract:
An HGF production accelerator containing as an active ingredient an oligosaccharide which is any of a 2-saccharide comprising a uronic acid residue (the uronic acid is iduronic acid or glucuronic acid; the same applies hereinafter) and a glucosamine residue bonded to the uronic acid residue through an &agr -1,4-glycoside bond or β-1,4-glycoside bond, 3- to 16-saccharides each having a structure in which a uronic acid residue and a glucosamine residue have been alternatively bonded repeatedly through an &agr -1,4-glycoside bond or β-1,4-glycoside bond, and salts of these, wherein at least one hydroxy group of the uronic acid residue(s) and glucosamine residue(s) may have been sulfated, alkylated, acylated, or aminated and the 2-position amino group of at least one glucosamine residue may have been sulfated, alkylated, or acylated. The HGF production accelerator is useful for accelerating the treatment of disorders of tissues, organs, etc. of the living body.

Inventors:
NAKAMURA TOSHIKAZU (JP)
MATSUMOTO KUNIO
FUKUTA KAZUHIRO
Application Number:
PCT/JP2005/005741
Publication Date:
October 06, 2005
Filing Date:
March 28, 2005
Export Citation:
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Assignee:
NAKAMURA TOSHIKAZU (JP)
KRINGLE PHARMA INC (JP)
International Classes:
A61K31/7016; A61K31/702; A61K31/715; A61P1/16; A61P7/04; A61P11/00; A61P17/00; A61P17/02; A61P19/10; A61P25/00; A61P27/02; A61P35/00; A61P43/00; C07H11/00; C08B37/10; (IPC1-7): A61K31/715; A61K31/7016; A61K31/702; A61P1/16; A61P7/04; A61P11/00; A61P17/00; A61P17/02; A61P19/10; A61P25/00; A61P27/02; A61P35/00; A61P43/00; C07H11/00; C08B37/10
Domestic Patent References:
WO2002083700A22002-10-24
WO2003022291A12003-03-20
WO1999026984A11999-06-03
Foreign References:
JPH08506322A1996-07-09
JPH06506973A1994-08-04
JPH04503950A1992-07-16
JPS6366192A1988-03-24
JPH10218902A1998-08-18
JPH0892104A1996-04-09
JPH06312941A1994-11-08
JPH06507635A1994-09-01
JP2002003384A2002-01-09
JP2002327002A2002-11-15
JPH0834801A1996-02-06
Attorney, Agent or Firm:
Iwatani, Ryo (1-31 Dojima 2-chome, Kita-k, Osaka-shi Osaka, JP)
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