Title:
HIGH PURIFIED (2Β,3Α,5Α,16Β,17Β) -2-(4-MORPHOLINYL)-16-(1-PYRROLIDINYL)-ANDROSTANE-3,17-DIOL OR COMPOSITION CONTAINING IT AND ITS PREPARATION METHOD
Document Type and Number:
WIPO Patent Application WO/2010/118699
Kind Code:
A1
Abstract:
High purified (2β,3α,5α,16β,17β) -2-(4-morpholinyl)-16-(1-pyrrolidinyl)-androstane-3,17-diol (formula III) or composition containing it and their use in preparing rocuronium bromide (formula I) are disclosed.
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Inventors:
XIE FENG (CN)
XING NAIGUO (CN)
ZHANG WEI (CN)
GONG HENGYUAN (CN)
LIU ZERONG (CN)
DENG JIE (CN)
LUO JIE (CN)
YE WENRUN (CN)
FAN BIN (CN)
XING NAIGUO (CN)
ZHANG WEI (CN)
GONG HENGYUAN (CN)
LIU ZERONG (CN)
DENG JIE (CN)
LUO JIE (CN)
YE WENRUN (CN)
FAN BIN (CN)
Application Number:
PCT/CN2010/071820
Publication Date:
October 21, 2010
Filing Date:
April 16, 2010
Export Citation:
Assignee:
CHONGQING PHARM RES INST CO (CN)
XIE FENG (CN)
XING NAIGUO (CN)
ZHANG WEI (CN)
GONG HENGYUAN (CN)
LIU ZERONG (CN)
DENG JIE (CN)
LUO JIE (CN)
YE WENRUN (CN)
FAN BIN (CN)
XIE FENG (CN)
XING NAIGUO (CN)
ZHANG WEI (CN)
GONG HENGYUAN (CN)
LIU ZERONG (CN)
DENG JIE (CN)
LUO JIE (CN)
YE WENRUN (CN)
FAN BIN (CN)
International Classes:
C07J43/00; A61P21/02
Domestic Patent References:
| WO2007073424A1 | 2007-06-28 |
Other References:
ZHANG LONG-TAO ET AL.: "Study on the Synthetic Technique of Rocuronium Bromide", PERIODICAL OF OCEAN UNIVERSITY OF CHINA, vol. 37, July 2007 (2007-07-01), pages 147 - 150
Attorney, Agent or Firm:
UNITALEN ATTORNEYS AT LAW (Scitech PlaceNo. 22, Jian Guo Men Wai Ave.,Chao Yang District, Beijing 4, CN)
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