HIV INTEGRASE INHIBITORS - BRISTOL MYERS SQUIBB CO

Title:

HIV INTEGRASE INHIBITORS

Document Type and Number:

WIPO Patent Application WO2003049690

Kind Code:

A3

Abstract:

The present invention relates to the inhibition of HIV integrase, and to the treatment of AIDS or ARC by administering compounds of the following formula, or a tautomer of said compound, or a pharmaceutically acceptable salt, solvate or prodrug thereof: (formula I) wherein R<1>, R<2> and B<1> are as defined herein.

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Inventors:

WALKER MICHAEL A
BANVILLE JACQUES
REMILLARD ROGER
PLAMONDON SERGE

Application Number:

PCT/US2002/039092

Publication Date:

January 22, 2004

Filing Date:

December 06, 2002

Export Citation:

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Assignee:

BRISTOL MYERS SQUIBB CO (US)

International Classes:

A61K31/194; A61K31/195; A61K31/216; A61K31/275; A61K31/277; A61K31/335; A61K31/365; A61K31/443; A61K31/506; A61K31/5377; A61K31/55; A61K31/551; A61K45/00; A61K45/06; A61P31/18; A61P43/00; C07C51/16; C07C59/90; C07C205/00; C07C229/00; C07C239/20; C07C251/48; C07C255/64; C07C259/06; C07C259/10; C07D295/185; C07D317/00; C07D317/26; C07D317/34; C07D405/12; C07D413/12; (IPC1-7): C07C229/00; C07C59/90; C07C205/00

Other References:

DATABASE CAPLUS [online] USUI H. ET AL.: "Preparation of tartaric acid derivatives as squalens synthase inhibitors", XP002964974, accession no. STN Database accession no. 132:78549

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