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Title:
HIV REPLICATION INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2013/062028
Kind Code:
A1
Abstract:
Provided are a novel compound having an antiviral effect, particularly HIV replication-inhibiting activity, and a medical drug, particularly an anti-HIV drug, containing the same. The compound is represented by Formula (I) (where the broken line shows whether or not a bond is present; R1 is an optionally substituted alkyl, and the like; R2 is an optionally substituted alkyloxy, and the like; n is 1 or 2; R3 is an optionally substituted aromatic carbocyclic group, and the like; R4 is a hydrogen atom, and the like; R5 is an optionally aromatic carbocyclic group, and the like; Y is a single bond, and the like; R6 is an optionally substituted alkyl, and the like; R7 is -Z-R71, and the like; Z is -NR72-CO, and the like; R71 is an optionally substituted alkyl, and the like; and R72 is a hydrogen atom and the like).

Inventors:
IWAKI TSUTOMU (JP)
TOMITA KENJI (JP)
Application Number:
JP2012/077544
Publication Date:
May 02, 2013
Filing Date:
October 25, 2012
Export Citation:
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Assignee:
SHIONOGI & CO., LTD. (1-8 Doshomachi 3-chome, Chuo-ku Osaka-sh, Osaka 45, 〒5410045, JP)
International Classes:
C07C205/56; A61K31/192; A61K31/27; A61P31/18; C07C229/40; C07C233/33; C07C233/63; C07C233/81; C07C255/57; C07C271/22; C07C275/42; C07C311/14; C07C311/19
Domestic Patent References:
WO2010055911A12010-05-20
WO2007020936A12007-02-22
WO2009052319A12009-04-23
WO2012140243A12012-10-18
WO2008071587A22008-06-19
WO2007131350A12007-11-22
WO2009062285A12009-05-22
WO2009062288A12009-05-22
WO2009062289A12009-05-22
WO2009062308A12009-05-22
WO2010130034A12010-11-18
WO2010130842A12010-11-18
WO2011015641A12011-02-10
WO2011076765A12011-06-30
WO2012033735A12012-03-15
WO2012003497A12012-01-05
WO2012003498A12012-01-05
WO2012066442A12012-05-24
WO2012102985A12012-08-02
WO2012137181A12012-10-11
WO2012140243A12012-10-18
WO2010055911A12010-05-20
Foreign References:
EP2374790A12011-10-12
JP2010195727A2010-09-09
EP2402305A12012-01-04
JP2009530306A2009-08-27
US20090312323A12009-12-17
JP2011146118A2011-07-28
JP2011176630A2011-09-08
JP2012095869A2012-05-24
Other References:
See also references of EP 2772480A4
GIT FACHZEITSCHRIFT FUER DAS LABORATORIUM, vol. 27, no. 12, 1983, pages 1078 - 1080
AUSTRALIAN JOURNAL OF CHEMISTRY, vol. 64, no. 6, 2011, pages 757 - 765
ACTA CRYSTALLOGRAPHICA, SECTION C, vol. C46, no. 12, 1990, pages 2486 - 2487
SYNLETT, 1990, pages 697 - 699
JOURNAL OF ORGANIC CHEMISTRY, vol. 52, no. 2, 1987, pages 296 - 298
JOURNAL OF NATURAL PRODUCTS, vol. 67, no. 7, 2004, pages 1172 - 1174
"Isotopes in the Physical and Biomedical Sciences", vol. 1, 1987
"Design of Prodrugs", 1985, ELSEVIER
Attorney, Agent or Firm:
TAKAYAMA, Hirotsugu et al. (Shionogi & Co, Ltd. Intellectual Property Department 1-1, Futabacho 3-chome, Toyonaka-sh, Osaka 25, 〒5610825, JP)
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Claims: