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Title:
HIV REPLICATION INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2014/119636
Kind Code:
A1
Abstract:
Provided are: a novel compound which has an antiviral effect, in particular, HIV replication inhibitory activity; and a pharmaceutical product, in particular, an anti-HIV agent which contains the novel compound. A compound which is represented by formula (I) (wherein ring A represents a substituted or unsubstituted carbon ring or a substituted or unsubstituted heterocyclic ring; R1 represents a substituted or unsubstituted alkyl group or the like; R2 represents a substituted or unsubstituted alkyloxy group or the like; n represents 1 or 2; R3 represents a substituted or unsubstituted carbocyclic group or a substituted or unsubstituted heterocyclic group; R4 represents a hydrogen atom or the like; and R6 represents a substituted or unsubstituted alkyl group or the like).

Inventors:
TOMITA KENJI (JP)
TAODA YOSHIYUKI (JP)
IWAKI TSUTOMU (JP)
KAWASUJI TAKASHI (JP)
AKIYAMA TOSHIYUKI (JP)
SUGIYAMA SHUICHI (JP)
TAMURA YOSHINORI (JP)
IWATSU MASAFUMI (JP)
Application Number:
PCT/JP2014/052030
Publication Date:
August 07, 2014
Filing Date:
January 30, 2014
Export Citation:
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Assignee:
SHIONOGI & CO (JP)
International Classes:
C07D209/58; A61K31/395; A61K31/403; A61K31/4184; A61K31/4439; A61K31/473; A61K31/4741; A61K31/4743; A61K31/4745; A61K31/538; A61K31/5383; A61K31/5415; A61K31/55; A61K31/554; A61P31/18; A61P43/00; C07D221/12; C07D223/18; C07D225/08; C07D279/02; C07D281/02; C07D405/04; C07D405/14; C07D413/04; C07D417/04; C07D491/048; C07D495/04; C07D495/14; C07D498/04
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Foreign References:
EP2511273A12012-10-17
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Other References:
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 133, no. 45, 2011, pages 18183 - 18193
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 130, no. 52, 2008, pages 17676 - 17677
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 12, no. 2, 1977, pages 161 - 171
"Isotopes in the Physical and Biomedical Sciences", vol. 1, 1987, article "Labeled Compounds"
"Design of Prodrugs", 1985, ELSEVIER
Attorney, Agent or Firm:
TAKAYAMA, Hirotsugu et al. (JP)
Hiromitsu Takayama (JP)
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