Title:
HLA-A24-RESTRICTED EPITOPE PEPTIDE DERIVED FROM METHOTHELIN
Document Type and Number:
WIPO Patent Application WO/2019/078296
Kind Code:
A1
Abstract:
Provided is an HLA-A24-restricted epitope peptide derived from methothelin. More specifically, provided are a peptide comprising an amino acid sequence AFYPGYLCSL (SEQ ID NO: 15), a polynucleotide encoding the peptide represented by SEQ ID NO: 15, and an expression vector containing the polynucleotide.
Inventors:
YAMAUE HIROKI (JP)
HIRONO SEIKO (JP)
WADA SATOSHI (JP)
HIRONO SEIKO (JP)
WADA SATOSHI (JP)
Application Number:
PCT/JP2018/038829
Publication Date:
April 25, 2019
Filing Date:
October 18, 2018
Export Citation:
Assignee:
WAKAYAMA MEDICAL UNIV (JP)
KANAGAWA PREFECTURAL HOSPITAL ORGANIZATION (JP)
KANAGAWA PREFECTURAL HOSPITAL ORGANIZATION (JP)
International Classes:
C12N15/11; A61K38/08; A61P35/00; A61P35/04; C07K7/06; C12N5/0783; C12N5/0784
Foreign References:
| JP2014521657A | 2014-08-28 |
Other References:
TSUKAGOSHI, MARIKO ET AL.: "Identification of a novel HLA- A24-restricted cytotoxic T lymphocyte epitope peptide derived from mesothelin in pancreatic cancer", ONCOTARGET, vol. 9, no. 59, 31 July 2018 (2018-07-31), pages 31448 - 31458, XP055597344, DOI: doi.org/10.18632/oncotarget.25837
Attorney, Agent or Firm:
YAMAO, Norihito et al. (JP)
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