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Title:
HOLLOW FIBER MEMBRANE MODULE FOR USE IN PRODUCTION OF CHEMICAL SUBSTANCE, AND PROCESS FOR PRODUCTION OF CHEMICAL SUBSTANCE
Document Type and Number:
WIPO Patent Application WO/2011/058983
Kind Code:
A1
Abstract:
Disclosed is a hollow fiber membrane module (1) for use in the production of a chemical substance, which can be used in the continuous fermentation that comprises filtrating a fermentation culture of a microorganism or a cultured cell through a hollow fiber membrane, collecting a chemical substance from a filtrate, retaining a concentrated solution in the fermentation culture or refluxing the concentrated solution, and further adding a fermentation raw material to the fermentation culture. In the hollow fiber membrane module (1), multiple hollow fiber membrane bundles are accommodated in a tubular case, at least one end part of each of the hollow fiber membrane bundles is fixed onto the tubular case in such a manner that the end surface of each of the hollow fiber membranes is opened by means of a hollow-fiber-membrane-bundling material, and the hollow-fiber-membrane-bundling material comprises a synthetic resin that exhibits a hardness retention rate of 95% or more after the material is brought into contact with a saturated water vapor at 121°C for 24 hours. The hollow fiber membrane module (1) can keep substance productivity at a high level and can be used in the production of a chemical substance by a sterilizable continuous fermentation method.

Inventors:
TAKEUCHI NORIHIRO (JP)
MINEGISHI SHIN-ICHI (JP)
CHEON JIHOON (JP)
NISHIDA MAKOTO (JP)
MIMITSUKA TAKASHI (JP)
SUZUKI HIRONOBU (JP)
YAMADA KATSUSHIGE (JP)
SAWAI HIDEKI (JP)
KUMO ICHIRO (JP)
Application Number:
PCT/JP2010/069969
Publication Date:
May 19, 2011
Filing Date:
November 10, 2010
Export Citation:
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Assignee:
TORAY INDUSTRIES (JP)
TAKEUCHI NORIHIRO (JP)
MINEGISHI SHIN-ICHI (JP)
CHEON JIHOON (JP)
NISHIDA MAKOTO (JP)
MIMITSUKA TAKASHI (JP)
SUZUKI HIRONOBU (JP)
YAMADA KATSUSHIGE (JP)
SAWAI HIDEKI (JP)
KUMO ICHIRO (JP)
International Classes:
B01D63/04; B01D63/00; B01D71/34; C12M1/12; C12M3/06; C12N15/09; C12P7/56
Foreign References:
JP2008237101A2008-10-09
JP2008099667A2008-05-01
JP2010029108A2010-02-12
JP2007252367A2007-10-04
JP2008237101A2008-10-09
JPH0760074A1995-03-07
JP2005230813A2005-09-02
Other References:
TOSHIHIKO HIRAO, APPL. MICROBIOL. BIOTECHNOL., vol. 32, 1989, pages 269 - 273
See also references of EP 2500083A4
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