Title:
HOLLOW POROUS SPHERICAL PARTICLE ARTIFICIAL BONE, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/153794
Kind Code:
A1
Abstract:
Disclosed is a method for preparing a hollow porous spherical particle artificial bone, the method involving: (1) uniformly mixing a bioceramic powder, a bioglass powder and an excipient to obtain a solid phase mixture, then adding a binder solution to the solid phase mixture, and uniformly mixing same to obtain a plastic wet material; (2) loading the plastic wet material into an extrusion device of an extrusion rounder, and extruding same through an orifice plate of the extrusion device to form a strip-shaped material; (3) placing the strip-shaped material into a rounding device of the extrusion rounder, cutting same, and then rounding same into spherical particles; and (4) placing the spherical particles into a furnace, degreasing same to remove the excipient and the binder, and then sintering same at 750℃-1550℃. Further disclosed are a hollow porous spherical particle artificial bone prepared by means of the preparation method and the use thereof. The obtained artificial bone has a hollow structure, a large number of macropores and micropores, a controllable pore structure, a high porosity, and a high strength, and has a good application prospect in the field of bone defect repair materials.
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Inventors:
YE JIANDONG (CN)
HE FUPO (CN)
HE FUPO (CN)
Application Number:
PCT/CN2018/111612
Publication Date:
August 15, 2019
Filing Date:
October 24, 2018
Export Citation:
Assignee:
UNIV SOUTH CHINA TECH (CN)
International Classes:
A61L27/10; A61L27/56
Foreign References:
CN108324987A | 2018-07-27 | |||
CN106563170A | 2017-04-19 | |||
CN106390190A | 2017-02-15 | |||
CN103113129A | 2013-05-22 | |||
CN103893829A | 2014-07-02 | |||
EP1516635A1 | 2005-03-23 |
Attorney, Agent or Firm:
GUANGZHOU HUAXUE INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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