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Title:
HOLOGRAPHIC CHARACTERIZATION OF PROTEIN AGGREGATES
Document Type and Number:
WIPO Patent Application WO/2017/139279
Kind Code:
A3
Abstract:
Systems and methods for holographic characterization of protein aggregates. Size and refractive index of individual aggregates in a solution can be determined. Information regarding morphology and porosity can be extracted from holographic data.

Inventors:
GRIER, David G. (120 West 15th Street, New York, New York, 10011, US)
WARD, Michael D. (120 West 15th Street, Apartment 5CNew York, New York, 10011, US)
ZHONG, Xiao (40 Newport Parkway, Apartment 1910Jersey City, New Jersey, 07310, US)
WANG, Chen (726 Broadway, New York, New York, 10003, US)
PHILIPS, Laura A. (330 East 38th Street, #48JNew York, New York, 10016, US)
RUFFNER, David B. (330 East 38th Street, #48JNew York, New York, 10016, US)
CHEONG, Fook Chiong (269 Greene Street, Apt. ENew York, New York, 10003, US)
Application Number:
US2017/016857
Publication Date:
October 26, 2017
Filing Date:
February 07, 2017
Export Citation:
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Assignee:
NEW YORK UNIVERSITY (70 Washington Square South, New York, New York, 10012, US)
International Classes:
G01B9/02; G01N15/02; G01N15/10; G01N21/41; G01P5/20; G03H1/08
Foreign References:
US20140333935A12014-11-13
US20140177932A12014-06-26
US20150062587A12015-03-05
US20040072372A12004-04-15
Other References:
MEAKIN: "Fractal Aggregates", ADVANCES IN COLLOID AND INTERFACE SCIENCE, vol. 28, 1988, pages 249 - 331, XP055574701, Retrieved from the Internet [retrieved on 20170524]
Attorney, Agent or Firm:
MARTIN, Matthew E. et al. (FOLEY & LARDNER LLP, 3000 K Street N.W.Suite 60, Washington District of Columbia, 20007, US)
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