Title:
HOMEODOMAIN-INTERACTING PROTEIN KINASES AND THE USE OF THE SAME FOR INFLUENCING CELL DIVISION AND CELL PROLIFERATION
Document Type and Number:
WIPO Patent Application WO2002057433
Kind Code:
A9
Abstract:
The invention relates to the use of homeodomain-interacting protein kinases (HIPKs), especially HIPK2, and the nucleic acid sequences coding for the same, for influencing cell division and cell proliferation, and especially the use thereof in methods for diagnosing or treating diseases associated with anomalous or excessive cell proliferation e.g. tumour diseases. The invention also relates to the use of HIPKs, especially HIPK2, the nucleic acid sequences coding for the same and specific bonding partners thereof, for identifying and/or producing substances which can inhibit or stimulate cell division or cell growth or influence the same in other ways. The invention especially relates to a human HIPK2 and derivatives and fragments thereof, the nucleic acid sequences coding for the same, and antibodies and other specific bonding partners of the human HIPK2 and the nucleic acid sequence coding for the same.
Inventors:
HOFMANN THOMAS (DE)
SCHMITZ LIENHARD (DE)
DROEGE WULF (DE)
MOELLER ANDREAS (DE)
WILL HANS (DE)
HUESEYIN SIRMA (DE)
SCHMITZ LIENHARD (DE)
DROEGE WULF (DE)
MOELLER ANDREAS (DE)
WILL HANS (DE)
HUESEYIN SIRMA (DE)
Application Number:
PCT/EP2002/000557
Publication Date:
October 31, 2002
Filing Date:
January 21, 2002
Export Citation:
Assignee:
DEUTSCHES KREBSFORSCH (DE)
HOFMANN THOMAS (DE)
SCHMITZ LIENHARD (DE)
DROEGE WULF (DE)
MOELLER ANDREAS (DE)
WILL HANS (DE)
HUESEYIN SIRMA (DE)
HOFMANN THOMAS (DE)
SCHMITZ LIENHARD (DE)
DROEGE WULF (DE)
MOELLER ANDREAS (DE)
WILL HANS (DE)
HUESEYIN SIRMA (DE)
International Classes:
C12N1/21; C12N9/12; C12N15/54; (IPC1-7): C12N9/12
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