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Title:
HOMOZYGOTE HAPLOTYPE METHOD
Document Type and Number:
WIPO Patent Application WO/2008/018240
Kind Code:
A1
Abstract:
To provide a method of efficiently searching for a disease sensitivity gene and an apparatus therefor. It is intended to provide: a method of determining a homoeologous region which comprises the polymorphism marker selection step of selecting a polymorphism marker usable as the subject of the homozygote determination, the homozygote determination step of determining whether or not bases constituting a specimen DNA which is a diploid or higher are homozygous, the homozygote haplotype data acquisition step of selecting exclusively polymorphism markers determined as homozygous and acquiring homozygote haplotype data of each specimen, the homozygous region data acquisition step of comparing the above-described homozygote haplotype data of two or more specimens and acquiring common homozygous region data, and the homoeologous region determination step of determining a common homozygous region satisfying definite homoeology requirements as a homoeologous region between the corresponding specimens for each common homozygous region data; and an apparatus and a gene screening method with the use of this method.

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Inventors:
HAGIWARA, Koichi (113-5, Nakashinden Turugashima-shi, Saitama 26, 3502226, JP)
Application Number:
JP2007/062368
Publication Date:
February 14, 2008
Filing Date:
June 13, 2007
Export Citation:
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Assignee:
TOMY DIGITAL BIOLOGY CO., LTD. (3-14-17, Tagara Nerima-ku, Tokyo 73, 1790073, JP)
トミーデジタルバイオロジー株式会社 (〒73 東京都練馬区田柄３丁目１４－１７ Tokyo, 1790073, JP)
Saitama Medical University (38 Morohongo, Moroyama-machiIruma-gun, Saitama 95, 3500495, JP)
International Classes:
C12N15/09; C12M1/00; C12Q1/68; C12N15/09; C12M1/00; C12Q1/68
Attorney, Agent or Firm:
KUDO, Ichiro (Yurakucho Denki Bldg. South Tower, 7-1 Yurakucho 1-chom, Chiyoda-ku Tokyo 06, 1000006, JP)
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